Marín de Mas, Igor Bartolomé (Date of defense: 2015-03-20)
The general aim of this thesis is to develop and apply new computational tools to overcome existing limitations in the analysis of metabolism. This thesis is focused on developing new computational ...
Serra Mas, Montserrat (Date of defense: 2006-11-23)
En la natura, la comunicació entre espècies o individus d'una mateixa espècie es produeix per l'emissió i captació per part dels diferents individus de compostos específics. Aquests compostos químics ...
Álvarez Marimón, Mª Elena (Date of defense: 2014-10-27)
Heteromeric amino acid transporters (HATs) mediate the transport of amino acids through the plasma membrane. They are composed of two subunits (a heavy and a light one) linked by a conserved disulfide ...
Arimany Nardi, Cristina (Date of defense: 2013-12-03)
Nucleoside-derived drugs are used for the treatment of haematological malignancies, viral infections and autoimmune or inflammatory diseases. These drugs require membrane transporters to be internalised ...
Cereijo Téllez, Rubén (Date of defense: 2015-12-17)
El teixit adipós ha passat d’ésser considerat un mer reservori d’energia a un òrgan complex, implicat de forma activa en l’homeòstasi energètica i amb funcions endocrines de rellevància. Les malalties ...
Benito Mauricio, Adrián (Date of defense: 2014-02-21)
The present doctoral thesis is focused on the metabolic adaptations induced by oncogene activation as well as the potential role of the metabolic network as antitumor therapy. Over the last years, it ...
Codó Tarraubella, Laia (Date of defense: 2019-12-03)
Recently, research processes in Life sciences have evolved at a rapid pace. This evolution, mainly due to technological advances, offers more powerful equipment and generalizes the digital format of ...
Rotondo, Floriana (Date of defense: 2018-02-19)
The current theories about endothelial inflammation in the adipose tissue in metabolic syndrome point to hypoxia as one of its main causes. Nevertheless, our group has found that both 3T3L1 adipocytes, ...
Giménez Oya, Víctor (Date of defense: 2009-12-09)
Los isoprenoides son una de las mayores familias de compuestos descritos en la naturaleza. Estos compuestos están presentes en todos los organismos vivos y se sintetizan a partir de dos moléculas de 5 ...
Grañé Boladeras, Natàlia (Date of defense: 2012-12-21)
hENT2 is the human nucleoside transporter for which most splice variants have been described to date, in contrast to hENT1 for which no variants have been reported yet. In this dissertation, we have ...