Meo Evoli, Nathalie (Date of defense: 2014-07-07)
The oncogenic properties of E2F1 have been traditionally associated with the role of the oncogene in proliferation, but during the last few years many other functions associated with this family of ...
Pulice, Giuseppe (Date of defense: 2014-12-15)
Changes in diet and life style caused an alarming increase in the incidence of obesity, which is considered a major risk factor for the onset of the metabolic syndrome. One of the initial events in ...
Calderone, Vittorio (Date of defense: 2013-07-19)
Hepatic cirrhosis is a largely diffused pathology caused by alcohol abuse and hepatitis C in developed countries, whereas hepatitis B is the cause in most parts of Asia and sub-Saharan Africa. It's ...
Tnani, Hédia (Date of defense: 2012-07-18)
The embryo in grasses, at grain maturity, comprises the embryonic axis and the scutellum. The scutellum is supposed to be the single cotyledon in the monocotyledoneus embryos and is attached to the ...
Solé Ferré, Anna (Date of defense: 2016-03-04)
This work is focused on the study of Polypurine Reverse Hoogsteen (PPRH) hairpins and their ability as gene correction tools. The repair of a point mutation at its endogenous gene locus has been the ...
Sdelci, Sara (Date of defense: 2012-12-13)
This thesis project is focused on the study of the signaling module formed by the NIMA-related protein Nek6, Nek7, and Nek9 and their function during early mitosis, with particular interest in centrosome ...
Martrus Zapater, Gloria (Date of defense: 2013-07-10)
Human immunodeficiency virus type 1 (HIV-1) has a biased nucleotide composition different from human genes. This raises the question of how evolution has chosen the nucleotide sequence HIV-1 observed ...
Lanuza Masdeu, Jordi (Date of defense: 2013-04-05)
Es va generar un ratolí transgènic amb la capacitat d'activar JNK específicament al pàncrees. Tot i que aquests ratolins no tenen cap afectació morfoestructural en els seus illots pancreàtics ni diferències ...
López Pelegrín, Maria del Mar (Date of defense: 2015-11-13)
Metallopeptidases are major players in the physiology and pathology of all living organisms. Their exquisite regulation is therefore essential for proper function and to prevent misdirected temporal ...
Malandrino, Maria Ida (Date of defense: 2013-10-04)
Current lifestyle with high-energy diets and little exercise is triggering an alarming growth in obesity. Excess of adiposity is leading to severe increase in associated pathologies, such as insulin ...