A liquid-to-solid transition governs neuronal mechanotransduction during touch in Caenorhabditis elegans 

    Sanfeliu Cerdán, Neus (Date of defense: 2024-03-12)

    (English) In recent years, our understanding of the ion channels and receptors that orchestrate the conversion of physical stimuli into physiological signals has deepened significantly. Nevertheless, there remains some ...

    A machine learning ride in the physics theme park: from quantum to biophysics 

    Requena Pozo, Borja (Date of defense: 2024-04-24)

    (English) The integration of artificial intelligence into research is propelling progress and discoveries across the entire scientific landscape. Artificial intelligence tools boost the development of novel scientific ...

    Active control of surface plasmons in hybrid nanostructures 

    Randhawa, Sukanya (Date of defense: 2012-12-04)

    Plasmonics nanostructures are becoming remarkably important as tools towards manipulating photons at the nanoscale. They are poised to revolutionize a wide range of applications ranging from integrated optical circuits, ...

    Advanced single molecule fluorescent tools to reveal spatiotemporal multi-molecular interactions in living cells 

    Mateos Estévez, Nicolás (Date of defense: 2023-04-28)

    (English) The spatiotemporal organisation and compartmentalisation of molecules in living cells is crucial to regulate cell function. Dysregulation in how molecules dynamically explore their environment and interact with ...

    Desarrollo y validación de una plataforma optofluídica ultrasensible para la detección especifíca y selectiva de mercadores tumorales en oncología 

    Ortega. M, María A. (Date of defense: 2015-11-11)

    Nowadays cancer is a devastating illness, so its early diagnosis could represent a powerful advantage in the struggle to eradicate it. The most recent technologies allowed the development of sensing platforms that led to ...

    Imaging and analytical tools to study the spatiotemporal dynamics of protein export 

    Angulo Capel, Jessica (Date of defense: 2024-10-18)

    (English) Intracellular trafficking, particularly protein secretion, faces numerous unresolved challenges. This thesis aims to provide and evaluate tools for quantitative investigation of these processes using fluorescent ...

    Membrane protein nanoclustering as a functional unit of immune cells : from nanoscopy to single molecule dynamics 

    Torreño Piña, Juan Andrés (Date of defense: 2015-10-02)

    State-of-the-art biophysical techniques featuring high temporal and spatial resolution have allowed for the first time the direct visualization of individual transmembrane proteins on the cell membrane. These techniques ...

    Molecular and cellular aspects of proprioceptive control in C. elegans 

    Malaiwong, Nawaphat (Date of defense: 2023-10-24)

    (English) Locomotion behavior is the output of the integrated clues by the nervous system along with proprioceptive regulation, which encompasses responses such as avoiding, feeding, and reproduction. Mechanosensation, the ...

    Statistical analysis and plasmonic effects to extend the use of Raman spectroscopy in biochemistry 

    Marro Sánchez, Mònica (Date of defense: 2013-07-12)

    Since its discovery in 1928, Raman spectroscopy (RS) has produced a revolution in the fields of analytical chemistry and molecular detection. Thanks to the latest technical advances, the expectations of the applicability ...