A Genome-wide CRISPR screen to identify novel pathways involved in reprogramming and x-chromosome reactivation 

Barrero Asencio, Mercedes (Date of defense: 2023-03-02)

During reprogramming of somatic cells into induced pluripotent stem cells (iPSCs), the epigenome needs to be reset. A prime example of this is the reversal of the silent state of the inactive X chromosome in female cells, ...