• Lipid droplet regulation by the differentially spliced proteins Osw5L and Osw5S 

  Johnsen, Lisa, 1987- (Data de defensa: 18-12-2016)

  Epithelial tissues undergo extensive remodeling during embryonic development. Recent studies have revealed that, in a number of developmental processes, epithelial remodeling is associated with pulsations of individual ...
• Identification of HIV-1 reactivating quinoline compounds as bromodomain inhibitors 

  Abner, Erik, 1986- (Data de defensa: 21-12-2016)

  Tras la infección por VIH-1, el establecimiento de un depósito de células T en reposo infectadas latentemente con VIH impide la erradicación del virus en pacientes. Para lograr la erradicación, la terapia retroviral existente ...
• RNF169 and RNF168 novel substrates of DYRK1A : connecting DYRK1A to DNA-damage repair 

  Roewenstrunk, Julia Maria, 1981- (Data de defensa: 19-12-2016)

  Gene dosage alterations of the kinase DYRK1A are linked to disease in humans. To better understand DYRK1A activities an interactome analysis was performed. RNF169, an E3-ubiquitin ligase key component of the cellular ...
• The Role of cyclin O in ER stress signalling 

  Balsiger, Alexander, 1975- (Data de defensa: 19-12-2014)

  We recently identified a novel cyclin called Cyclin O which is able to bind and activate Cdk1 and Cdk2 in response to intrinsic apoptotic stimuli like DNA damage or ER stress. Cyclin O has been shown to be involved in the ...
• Mechanisms of acquired resistance to anti-EGFR therapies in squamous cell carcinoma 

  Guix Arnau, Marta, 1974- (Data de defensa: 19-12-2017)

  Targeted therapies against the Epidermal Growth Factor Receptor (EGFR) are useful to treat many human cancers such as non-small cell lung cancer, colorectal cancer and head and neck cancer. However, the efficacy of such ...

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