• Translational control by the RNA-binding protein CSDE1 : Insights into a stimulatory role in translation elongation 

  Ní Chárthaigh, Róisín-Ana (Date of defense: 03-07-2020)

  RNA-binding proteins are potent regulators of post-transcriptional gene expression. Among the repertoire of RNAs bound by a particular RNA-binding protein, networks of co-ordinately regulated RNAs, or ‘regulons’, are ...
• Transcriptional and post-transcriptional regulation across biological units and time 

  Sodaei, Reza, 1988- (Date of defense: 22-05-2020)

  How do genomes generate different tissues, behaviours, individuals or species? We try to identify parts of the human transcriptome that we found only in a tissue. Then, we focus on inter-individual extreme transcriptomic ...
• Circadian regulation of macrophages in homeostasis and disease 

  Val Casals, Maria, 1993- (Date of defense: 09-07-2020)

  Els ritmes circadians són oscil·lacions diàries en paràmetres fisiològics necessaris per a què els organismes adaptin la seva activitat als cicles de llum i foscor. A nivell molecular, la maquinària circadiana consisteix ...
• Cannabidiol as a potential therapeutic strategy to reduce cocaine seeking in mice 

  Luján Pérez, Miguel Ángel, 1991- (Date of defense: 13-03-2020)

  Cocaine addiction is a chronic, relapsing disease characterized by the compulsive seeking and use of the drug despite its harmful consequences. Currently, there are no approved pharmacotherapies available for the treatment ...
• Determinants of the local mutation rate variability along the genome 

  Frigola Rissech, Joan, 1991- (Date of defense: 13-03-2020)

  The rate at which mutations accumulate along the genome is not uniform but influenced by factors such as chromatin compactness, replication time or transcription. Most of these factors create mutational biases that ...

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