Universitat Pompeu Fabra
Ara mostrant els elements 2261-2280 de 3499
In contrast to mammals, zebrafish do have the ability to regenerate their heart after injury. A better understanding of how regenerationcompetent species do so should help developing strategies to enhance human cardiac ...
En los últimos años hemos sido testigos de la identificación de múltiples familias de receptores inmunológicos. En este contexto encontramos la recientemente descrita familia IREM/CD300 localizada en la región cromosómica ...
Unlike characteristic HP1 proteins, the HP1c isoform of Drosophila melanogaster is a euchromatic protein. HP1c forms a complex with the zinc finger proteins ROW and WOC, which are crucial for HP1c function. In the present ...
DNA hypomethylation of repeats has been found in almost every tumor type studied. Hypomethylation of repetitive elements was shown to increase the likelihood of homologous recombination of these repeated sequences and thus ...
Aquesta tesi es centra en la identificació de les molècules de la xarxa de Turing que controla el patró dels dits en l'extremitat del ratolí. L’especificació dels dits ha estat explicada a la llum del model de Positional ...
La seqüenciació del genoma humà ha marcat una fita important en la història de la biologia. Com a conseqüència, la genètica i la genòmica han experimentat un progrés enorme. Això ha permès un millor coneixement tant de les ...
ABC (ATP-binding cassette) transporters are involved in translocate a wide spectrum of molecules across the lipid bilayer and some of them are associated with various diseases. They also have an important role in multidrug ...
Pluripotent cells are unique due to their developmental potential and the possibility to study them is the key step to understand human development. These cells are characterized by their ability to originate all the ...
The analysis of the microenvironment in CLL-like monoclonal B cell lymphocytosis (MBL) and early-stage chronic lymphocytic leukemia (CLL) is relevant for understanding the natural history of CLL. To this end, a total of ...
TRPV4 is a non-selective cation channel with a wide expression and multiple cellular and systemic functions. Described initially as an osmosensor, it can also be activated by temperature and cell swelling. Due to this ...
The present work aims at establishing the first bases for studying the insect oocyte polarity in a phylogenetically basal species, the cockroach Blattella germanica. Our approach was to choose some genes that have been ...
The molecular mechanisms regulating sperm differentiation (spermiogenesis) and maturation in fishes are largely unknown. In these oviparous species, the initiation of sperm motility is triggered by the osmolality of the ...
Muscle dysfunction and muscle wasting are major systemic manifestations of chronic conditions such as Chronic Obstructive Pulmonary Disease (COPD) and cancer. Several biological mechanisms contribute to such a dysfunction. ...
The scope of the present work was to investigate whether the protective role of the traditional Mediterranean diet (TMD), and virgin olive oil (VOO) rich in phenolic compounds (PC), towards cardiovascular disease can be ...
RNA splicing is the process of removal of introns from pre-mRNAs. It is carried out by the spliceosome, composed of five small nuclear ribonucleoproteins (snRNPs). Several small molecules with antitumor properties target ...
Regulation of msl2 translation is a key step in the modulation of X-chromosome dosage compensation. MSL2 is the limiting subunit of the dosage compensation complex, an assembly that promotes hyper-transcription of the ...
The endocannabinoid system is an endogenous neuromodulatory system that regulates a plethora of physiological functions, including the control of movement, memory, anxiety, and pain, among others. Cannabinoid compounds are ...
Esta tesis aborda cómo se construyó jurídicamente la monarquía de la Ley de Sucesión en la Jefatura del Estado (1947) en la España franquista desde una perspectiva tanto formal como doctrinal. Primero, considerando el ...
The present thesis focuses on three topics within the domain of consumer behavior: self-regulation, the psychological consequences of money, and consumption rituals. The first chapter, devoted to self-regulation, presents ...
This PhD dissertation aims to advance knowledge on monitoring employment-related health inequalities, focusing on arguably the two most relevant employment conditions in high-income regions like Europe, namely unemployment ...
