Now showing items 1534-1553 of 3254

    Impact of the mode of data collection on the quality of survey questions in social sciences 

    Revilla, Melanie (Date of defense: 2012-09-26)

    This dissertation studies the impact of the mode of data collection on the quality of answers to survey questions, defined as the product of reliability and validity. Using data from the Netherlands about different topics ...

    Impacto de la disfunción muscular y de los microorganismos resistentes en las exacerbaciones de la enfermedad pulmonar obstructiva crónica 

    Estirado Vera, Cristina (Date of defense: 2022-06-15)

    La Enfermedad Pulmonar Obstructiva crónica (EPOC) presenta afectación pulmonar y sistémica y periodos de exacerbación (AEPOC), que contribuyen a su progresión. En algunas ocasiones la AEPOC está causada por microorganismos ...

    Impacts of early-life vitamin D on child and adolescent health outcomes 

    Sangüesa Boix, Júlia (Date of defense: 2024-06-13)

    Els baixos nivells de vitamina D durant l’embaràs i els primers anys de la vida són freqüents en dones embarassades i en nadons i, a més, poden tenir implicacions per a la salut de l’infant a llarg termini. Malgrat això, ...

    Implicaciones clínicas y biológicas del déficit de hierro en pacientes con enfermedad pulmonar obstructiva crónica : Efectos tras la reposición con hierro carboximaltosa 

    Martín Ontiyuelo, Clara (Date of defense: 2022-01-28)

    El déficit de hierro (DH) podría jugar un papel en la enfermedad pulmonar obstructiva crónica (EPOC) dado que es fundamental en la bioenergética celular. Estudio 1: Se analizaron 18 pacientes EPOC con DH y 18 pacientes ...

    Implicaciones de la participación en grupos de apoyo online en el bienestar emocional y la salud física de las personas con diabetes: cómo el consulmo de información puede llevar a los pacientes a tomar decisiones erróneas sobre su enfermedad y qué hacer desde una aproximación comunicativa 

    Herrero, Noelia (Date of defense: 2022-03-07)

    The thesis “Implications of participation in online support groups on the emotional well-being and physical health of people with diabetes” is a compendium of three articles that critically and interrelatedly addresses the ...

    Implication of the disease-associated ORMDL3 in macrophage physiology 

    Kiefer, Kerstin (Date of defense: 2016-05-12)

    Genome-wide association studies linked increased ORMDL3 expression levels to several inflammatory diseases via single nucleotide polymorphisms. However, the pathophysiological mechanisms underlying this association are ...

    Improvements to incentives in incentive-driven blockchain technologies 

    McMenamin, Conor (Date of defense: 2023-03-17)

    In this thesis, we present a set of protocols in areas at the core of current blockchain technology literature; consensus, decentralized finance and distributed computing. These areas are bound by a critical dependency ...

    Improving detection capabilities of doping agents by identification of new phase I and phase II metabolites by LC-MS/MS 

    Gómez Castellà, Cristina (Date of defense: 2014-03-07)

    Metabolic studies of doping agents have been traditionally performed by using gas chromatography coupled to mass spectrometry (GC-MS). In the last years, liquid chromatography coupled to mass spectrometry (LC-MS) has ...

    Improving mathematical abilities by training numerical representations in children : the relation between learning mathematics and numerical cognition 

    Ferres Forga, Nuria (Date of defense: 2018-01-11)

    Improving mathematical abilities is important for educational systems and for society overall. We present two training regimes based on numerical representations. In Study 1, we show that a three-week computer-based ...

    Improving molecular diagnosis in myeloid neoplasms : The role of cell-free DNA 

    García Gisbert, Nieves (Date of defense: 2022-03-04)

    Myeloid malignancies are clonal diseases originated in myeloid hematopoietic stem cells that are frequently initiated by somatic mutations. The detection of genetic alterations has considerably improved the diagnostic ...

    Improving sound retrieval in large collaborative collections 

    Favory, Xavier (Date of defense: 2021-03-04)

    Capturing sounds on a recording medium to enable their preservation and reproduction started to be possible during the industrial revolution of the 19th century, originally achieved through mechanic and acoustic devices, ...

    Improving the accuracy and the efficiency of multiple sequence alignment methods 

    Kemena, Carsten (Date of defense: 2012-12-12)

    Sequence alignment is one of the basic methods to compare biological sequences and the cornerstone of a wide range of different analyses. Due to this privileged position at the beginning of many studies its accuracy is of ...

    Improving the recovery of genomic information from complex samples 

    Hernández Rodríguez, Jéssica (Date of defense: 2018-06-08)

    The innovation of genomics has progressed at pace with the development of high-throughput DNA sequencing technologies. Prior to the outbreak of next-generation sequencing, retrieving genetic information was limited to a ...

    Imprudencia inconsciente y derecho penal de la culpabilidad 

    Guanais de Aguiar Filho, Oliveiros (Date of defense: 2016-02-04)

    La discusión sobre la compatibilidad entre la imprudencia inconsciente y el principio de culpabilidad ha llamado la atención de la dogmática penal hace más de dos siglos. La primera parte de este trabajo presenta esta ...

    In silico analysis of regulatory motifs in gene promoters 

    Bellora Pereyra, Nicolás (Date of defense: 2010-02-26)

    Regulation of gene transcription is a complex process involving many different proteins, some of which bind in a sequence-specific manner to DNA motifs in the gene promoter. The need to maintain specific interactions between ...

    In silico modeling of protein-ligand binding 

    Varela Rial, Alejandro (Date of defense: 2022-02-21)

    The affinity of a drug to its target protein is one of the key properties of a drug. Although there are experimental methods to measure the binding affinity, they are expensive and relatively slow. Hence, accurately ...

    In silico tools to study diseases and polypharmacology through the lens of network medicine 

    Aguirre Plans, Joaquim (Date of defense: 2021-07-14)

    El funcionament intern de les cèl·lules pot entendre’s com un conjunt d’interaccions entre biomolècules, formant una xarxa que coneixem amb el nom d’interactoma. Els fàrmacs i malalties poden considerar-se pertorbacions ...

    In utero exposure to xenoestrogens, associated health outcomes and epigenetic mechanisms in children 

    Vilahur Chiaraviglio, Nadia (Date of defense: 2014-09-25)

    The prenatal period is a stage of special sensitivity to the adverse effects of environmental agents for the developing fetus. The human placenta is an organ that, in the interface between mother and fetus, plays a key ...

    In vitro reconstitution of the collective activities of motor protein complexes 

    Tassinari, Andrea (Date of defense: 2020-05-19)

    In-depth exploration of the syntactic capabilities of autoencoding language models for downstream applications 

    Pérez-Mayos, Laura (Date of defense: 2022-06-15)

    Pretrained Transformer-based language models have quickly replaced traditional approaches to model NLP tasks, pushing the state of the art to new levels, and will certainly continue to be very influential in the years ...