Now showing items 3147-3166 of 3265
Rubio Pérez, Carlota (Date of defense: 2017-11-28)
Cancer is a disease of the genome. The study of tumor genomic alterations is used to guide several precision medicine strategies, some approved and a large number under clinical development. On the other hand, the study ...
Pasqual, Elisa (Date of defense: 2019-12-03)
La aplicación de la radiación ionizante (RI) en ámbito médico ha llegado, sin duda, para salvar vidas. Sin embargo, hay una preocupación entre los expertos de salud pública y protección radiológica con relación al incremento ...
Moreno Lama, Lucía (Date of defense: 2020-01-16)
Los inhibidores de PARP han surgido como nuevas terapias basadas en el papel essencial de las Poly (ADP-ribosa) polimerasas PARP-1 y PARP-2 en la respuesta a daño en el DNA, explotando el efecto de las mismas en la célula ...
Ruiz Orera, Jorge (Date of defense: 2017-01-19)
Aquesta tesi investiga els mecanismes de formació i evolució de gens de novo utilitzant seqüenciació massiva de transcrits complerts i de fragments protegits per ribosomes. Hem identificat milers de gens de novo en humans ...
Grawenhoff, Julia (Date of defense: 2024-01-24)
The local translation of messenger RNAs (mRNAs) within different neuronal compartments is a prerequisite the formation of long-term memories. mRNAs are localized via active transport along microtubules, however, the ...
D'Altri, Teresa (Date of defense: 2013-07-26)
Simón Cosano, Pablo (Date of defense: 2011-11-03)
This thesis is focused on the nationalization of party systems in Western Europe and combines four different approaches. Despite the literature claiming that political decentralization reduces party system nationalization, ...
Nguyen, My Land Do (Date of defense: 2020-01-31)
The purpose of this dissertation is to systematically investigate the theoretical perspective that political power derives from socioeconomic power—a fundamental tenet of both sociological theories of assimilation and ...
Prado Peralta, María Gabriela (Date of defense: 2020-07-14)
Background: There is evidence suggesting that body weight is associated with lung function, but results are contradictory and suffer from important limitations. We aimed to assess the association of body weight and composition ...
Zadra, Ivan (Date of defense: 2022-03-17)
To ensure faithful segregation of the genetic material, cells build the mitotic spindle, a machinery made of dynamic microtubules (MTs) and MT associated proteins (MAPs). Chromosome bi-orientation is achieved through the ...
Santamaría-García, Hernando (Date of defense: 2014-01-31)
The present research is aimed at analyzing how human’s brain jointly computes cognitive and social interactions in presence of implicit social stimuli and/or in presence of socially neutral stimuli. First we analyzed the ...
Bogu, Gireesh K. (Date of defense: 2017-01-13)
Widespread transcription in mammals revealed unexpected discovery of non-coding elements like long noncoding RNAs (lncRNAs) and repetitive elements. First, lncRNAs were previously identified in limited number of tissues ...
Morron Salmeron, Adrià (Date of defense: 2017-05-30)
The existence of transportation costs gives labor markets a local dimension. In particular, the well-documented existence of agglomeration economies creates a positive correlation between a city's size and the productivity ...
Adelstein, Andreina (Date of defense: 2007-02-16)
Esta tesis estudia la especificidad de los significados léxicos especializados, a partir del análisis del funcionamiento de nombres relacionales; ofrece una explicación integrada de la semántica especializada y no especializada ...
Cornea, Ioana (Date of defense: 2015-05-18)
El objetivo de esta Tesis doctoral es identificar las unidades de conocimiento especializado del derecho de extranjería con el fin de representar la relación de la equivalencia en un diccionario bilingüe español-rumano ...
Bevilacqua, Cleci Regina (Date of defense: 2004-06-11)
Esta tesis tiene como objeto de estudio las Unidades Frasológicas Especializadas Eventiv as (UFE eventivas), definidas como unidades sintagmáticas formadas por uno o más términos, que se componen de un núcleo terminológico ...
Xu, Yingfeng (Date of defense: 2020-06-23)
Esta tesis doctoral tiene como finalidad principal analizar la situación de la enseñanza de la lengua china en España, concretamente en Barcelona, y en toda su complejidad, para proponer la introducción de léxico ...
Figueras Puig, Cristina (Date of defense: 2022-04-08)
Metastasis is the major cause of death from Breast Cancer (BCa). During its progression, divergent opinions have arisen regarding the hormonal status of the BCa subtypes. The mammary gland is composed of different cell ...
Jungfleisch, Jennifer (Date of defense: 2015-03-20)
Translation control is a vital aspect of gene expression for both viruses and their cellular hosts. We have previously shown that the cellular mRNA decay activators Dhh1 and Lsm1-7 promote translation of positive-strand ...
Stepniewski, Tomasz Maciej (Date of defense: 2020-01-09)
G protein-coupled receptors (GPCRs) are the main acceptors of neurotransmitters, and thus play an important role in communication between neurons. Because of this they are an attractive drug target for multiple neurodegenerative ...