Universitat Pompeu Fabra
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La seqüenciació del genoma humà ha marcat una fita important en la història de la biologia. Com a conseqüència, la genètica i la genòmica han experimentat un progrés enorme. Això ha permès un millor coneixement tant de les ...
ABC (ATP-binding cassette) transporters are involved in translocate a wide spectrum of molecules across the lipid bilayer and some of them are associated with various diseases. They also have an important role in multidrug ...
Pluripotent cells are unique due to their developmental potential and the possibility to study them is the key step to understand human development. These cells are characterized by their ability to originate all the ...
The analysis of the microenvironment in CLL-like monoclonal B cell lymphocytosis (MBL) and early-stage chronic lymphocytic leukemia (CLL) is relevant for understanding the natural history of CLL. To this end, a total of ...
TRPV4 is a non-selective cation channel with a wide expression and multiple cellular and systemic functions. Described initially as an osmosensor, it can also be activated by temperature and cell swelling. Due to this ...
The present work aims at establishing the first bases for studying the insect oocyte polarity in a phylogenetically basal species, the cockroach Blattella germanica. Our approach was to choose some genes that have been ...
The molecular mechanisms regulating sperm differentiation (spermiogenesis) and maturation in fishes are largely unknown. In these oviparous species, the initiation of sperm motility is triggered by the osmolality of the ...
Muscle dysfunction and muscle wasting are major systemic manifestations of chronic conditions such as Chronic Obstructive Pulmonary Disease (COPD) and cancer. Several biological mechanisms contribute to such a dysfunction. ...
The scope of the present work was to investigate whether the protective role of the traditional Mediterranean diet (TMD), and virgin olive oil (VOO) rich in phenolic compounds (PC), towards cardiovascular disease can be ...
RNA splicing is the process of removal of introns from pre-mRNAs. It is carried out by the spliceosome, composed of five small nuclear ribonucleoproteins (snRNPs). Several small molecules with antitumor properties target ...
Regulation of msl2 translation is a key step in the modulation of X-chromosome dosage compensation. MSL2 is the limiting subunit of the dosage compensation complex, an assembly that promotes hyper-transcription of the ...
The endocannabinoid system is an endogenous neuromodulatory system that regulates a plethora of physiological functions, including the control of movement, memory, anxiety, and pain, among others. Cannabinoid compounds are ...
Esta tesis aborda cómo se construyó jurídicamente la monarquía de la Ley de Sucesión en la Jefatura del Estado (1947) en la España franquista desde una perspectiva tanto formal como doctrinal. Primero, considerando el ...
The present thesis focuses on three topics within the domain of consumer behavior: self-regulation, the psychological consequences of money, and consumption rituals. The first chapter, devoted to self-regulation, presents ...
This PhD dissertation aims to advance knowledge on monitoring employment-related health inequalities, focusing on arguably the two most relevant employment conditions in high-income regions like Europe, namely unemployment ...
This doctoral thesis examines the legitimacy of secession in the context of liberal democracies. This is a recent debate in political theory since secession has been an excluded issue by liberal theories of democracy. ...
Aquest estudi es proposa interrogar-se sobre la noció de progrés moral en el marc del pragmatisme lingüístic de Richard Rorty per tal de contribuir en el debat acadèmic actual a l’entorn d’aquest concepte. Al temps que ...
This thesis investigates the Mexican regulatory reforms focusing on the evolution of the institutional arrangements of the regulatory state across policy regimes. It is based on a qualitative research design and the results ...
L’orella interna dels vertebrats és una estructura altament organitzada i complexa on cadascun dels específics tipus cel•lulars és generat a dominis concrets. Per aquest motiu, l’especificació cel•lular i la seva organització ...
Aquesta tesi proposa una estructura de dades per emmagatzemar imatges tridimensionals. L'estructura da dades té forma d'arbre i codifica les components connexes dels conjunts de nivell de la imatge. Aquesta estructura ...
