Universitat Pompeu Fabra
Now showing items 343-362 of 3276
Els cossos de processament (cossos-P) són grànuls discrets i dinàmics que contenen mRNAs represos en la traducció així com proteïnes involucrades en la degradació dels mRNAs i de la maquinària dels miRNAs. Alguns components ...
Este proyecto se centra en el papel de las células senescentes durante la regeneración muscular desde varios ángulos. Para llevarlo a cabo, hemos desarrollado una técnica novedosa para poder aislar células senescentes ...
Esta tesis estudia el sonido del cine estructural analizando sus fundamentaciones teóricas, sus tratamientos prácticos y sus apreciaciones estéticas. Se parte de una serie de películas estructurales internacionales englobadas ...
Durante la Edad del Bronce Tardío, el Levante Central estaba dividido en pequeños estados. La mayoría de los estudiosos creen que estos estados se organizaban de acuerdo con el modelo político y económico de la ciudad-estado, ...
Notre thèse se propose d’inventorier les thèmes qui découlent du motif des « eaux dormantes » −motif qui es un des traits caractéristiques de la littérature francophone décadente et symboliste (1860-1910)− dans une ...
The dissertation addresses how changes in gender norms influence demographic behaviors. It is composed of three articles. The first focuses on the macro-micro association between regional gender norms and couples' divorce ...
This thesis contributes to knowledge about gender differences in labor market attachment by using a longitudinal, life-course approach, and consists of three empirical articles. The first one establishes the profile of ...
Background: Walking is crucial for an active and healthy ageing. Aim: To understand walking in ageing populations, and, as a case study, in chronic obstructive pulmonary disease (COPD). Methods: This thesis (in seven ...
Dual-Spiral Dual-Energy Computed Tomography is an emerging technology that is being introduced in Radiotherapy Departments of hospitals because of its cost and simplicity. There is still a lack of literature about its ...
The usability of computer models of the heart depends mostly on their capacity to accurately represent heart anatomy, microstructure and function. However, integrating such a variety of biological data is often not possible. ...
G protein-coupled receptors (GPCRs) are central to cellular signaling and pivotal in drug development. This thesis investigates allosteric communication in GPCRs, crucial for their effective modulation in pharmacotherapy. ...
Autism Spectrum Disorder (ASD) is a group of neurodevelopmental disorders, the etiology of which is unknown in the majority of cases. Little is known about complex genomic regions containing part of the missing heritability. ...
La monoubiquitinación de la histona H2A cumple un rol esencial en la represión génica. Diversas enzimas desubiquitinantes (DUBs) han sido identificadas, que remueven específicamente la ubiquitina de H2A en distintos ...
The following thesis tries to answer the question of wheter RNA processing alterations are informative for the clinical management of cancer patients. For this, the work is focused on solve two main issues: the development ...
Human cytomegalovirus (HCMV) infection induces a persistent reconfiguration of the NK cell compartment in some individuals, promoting the development of a mature NK cell subset, hallmarked by high expression levels of ...
Notch activation in aortic endothelial cells (ECs) takes place at embryonic stages during cardiac valve formation and induces an endothelial-to-mesenchymal transition (EndMT). Using aortic ECs, we show here that active ...
La malaltia d’Alzheimer (MA) està precedida per una llarga etapa preclínica, en la qual es desenvolupa la patologia cerebral en absència de simptomatologia. La identificació acurada d’aquesta fase preclínica, i un millor ...
Pancreatic cancer is nowadays one of the neoplasms with worst prognosis, so research towards the discovery of new molecular targets for therapy and diagnosis is more than urgent. In this direction, we have deeply evaluated ...
We study two methods of data analysis which are common tools for the analysis of neuronal data. In particular, we examine how causal interactions between brain regions can be investigated using time series reflecting the ...
Chronic obstructive pulmonary disease (COPD) patients may present different types of systemic manifestations. Iron deficiency (ID) (Fe, an essential nutritional element) is common and can negatively affect exercise tolerance ...
