Now showing items 449-468 of 3213
Vandelli, Andrea (Date of defense: 2023-04-19)
Ribonucleoprotein condensates such as stress granules (SGs) and processing bodies (PBs) form in response to specific stimuli in the cell. Even though the key protein and RNA elements of these condensates are starting to ...
Bernardino, Gabriel (Date of defense: 2019-12-16)
We present a statistical shape analysis framework to identify cardiac shape remodelling while accounting for individual´s natural variability and apply it in two clinical applications: comparing triathletes with controls, ...
Piñero González, Janet (Date of defense: 2015-12-17)
In the last two decades, the volume and variety of biomedical data has dramatically increased. The data is heterogeneous and scattered across many resources. This produces bottlenecks in the analysis and extraction of ...
Pérez Llamas, Christian (Date of defense: 2015-12-18)
Given the complexity and heterogeneity of cancer, the development of new high-throughput wide-genome technologies has open new possibilities for its study. Several projects around the globe are exploiting these technologies ...
Gulati, Sankalp (Date of defense: 2016-11-17)
Automatically describing contents of recorded music is crucial for interacting with large volumes of audio recordings, and for developing novel tools to facilitate music pedagogy. Melody is a fundamental facet in most music ...
Cid Samper, Fernando (Date of defense: 2020-01-27)
Ribonucleoprotein granules (RNP granules) are liquid-liquid phase separated complexes composed mainly by proteins and RNA. They are responsible of many processes involved in RNA regulation. Alterations in the dynamics ...
López García de Lomana, Adrián (Date of defense: 2010-10-19)
Els mecanismes de regulaci o de les c el lules poden ser modelats per controlar i entendre la biologia cel lular. Diferents nivells d'abstracci o s'utilitzen per descriure els processos biol ogics. En aquest treball ...
Armaos, Alexandros (Date of defense: 2020-01-23)
Despite what was previously considered, the role of RNA is not only to carry the genetic information from DNA to proteins. Indeed, RNA has proven to be implicated in more complex cellular processes. Recent evidence ...
Cianferoni, Damiano (Date of defense: 2023-10-09)
Aquesta tesi presenta diversos avenços que inclouen: (i) noves funcionalitats afegides a la “suite” d'eines de disseny de proteïnes FoldX per permetre als usuaris treballar amb qualsevol tipus de molècula; (ii) estudis ...
Mill Tena, Jordi (Date of defense: 2022-10-14)
Atrial fibrillation is considered the most common arrhythmia in humans. Because the left atrium of the heart stops beating properly and begins to do so in an arrhythmic manner, the blood may become stagnant in a small ...
Mariotti, Marco (Date of defense: 2013-12-13)
Selenoproteins are a diverse class of proteins containing selenocysteine, the 21st aminoacid. Selenocysteine is inserted co-translationally, recoding very specific UGA codons through a dedicated machinery. Standard gene ...
Parra Farré, Genís (Date of defense: 2004-12-03)
El trabajo que aquí se presenta, estudia el reconocimiento de las señales que delimitan y definen los genes que codifican para proteínas, así como su aplicabilidad en los programas de predicción de genes. La tesis que aquí ...
Urru, Andrea (Date of defense: 2022-07-28)
Perinatal medicine has drawn increasing attention by the neuroscientific research community, as an early detection of most pathologies leads to more effective therapies and treatments. Monitoring fetal and neonatal brain ...
Bahrehmand, Arash (Date of defense: 2016-09-16)
Designing interior layouts is one of the most common elements of the immersive computer graphics projects (e.g., games, virtual reality and special effects). The design of 3D virtual environments aims to provide not only ...
Sayis, Batuhan (Date of defense: 2021-05-04)
Full-body Interaction experiences based on Mixed Reality (MR) systems are already playing an important role in encouraging socialization behaviors in children with Autism Spectrum Condition (ASC), as seen in the state of ...
Giraldo, Sergio Iván (Date of defense: 2016-09-16)
Computational modelling of expressive music performance deals with the analysis and characterization of performance deviations from the score that a musician may introduce when playing a piece in order to add expression. ...
Doste Beltrán, Rubén (Date of defense: 2019-11-18)
The purpose of this thesis was to develop personalised cardiovascular therapy guided by multimodal noninvasive imaging and simulations, combined with artificial intelligence tools, for the management of the outflow tract ...
Kranas, Hanna (Date of defense: 2023-11-03)
Living cells are exposed to naturally occurring DNA-damaging agents that promote the loss of genome integrity, threatening the proper functioning of the cell. To counteract the toxic accumulation of DNA damage, organisms ...
Bonet Giner, Jose (Date of defense: 2022-06-03)
Sequencing technologies have recently evolved and generated large amounts of data. These datasets have had significant impacts in the cancer field and the detection of damage and repair mechanisms. Methodologies to analyze ...
Gundem, Gunes (Date of defense: 2011-09-29)
In my thesis, I focused on integrative analysis of high-throughput oncogenomic data. This was done in two parts: In the first part, I describe IntOGen, an integrative data mining tool for the study of cancer. This system ...