RNF169 and RNF168 novel substrates of DYRK1A : connecting DYRK1A to DNA-damage repair 

Roewenstrunk, Julia Maria (Date of defense: 2016-12-19)

Gene dosage alterations of the kinase DYRK1A are linked to disease in humans. To better understand DYRK1A activities an interactome analysis was performed. RNF169, an E3-ubiquitin ligase key component of the cellular ...