Browsing Universitat Pompeu Fabra by Subject "616.5"

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Braquiterapia de superficie mediante moldes personalizados en cáncer de piel no melanoma

Membrive Conejo, Ismael (Date of defense: 2022-03-04)

La braquiterapia de superficie o plesioterapia es uno de los tratamientos recomendados en cáncer de piel localizado. Los estudios presentados en esta tesis tratan sobre nuestra experiencia con estos tratamientos. El ...

CACNA1A mutations with clinical relevance in migraine affect Cav2.1 channel regulation by G proteins and SNAREs

Serra Pascual, Selma A. (Date of defense: 2011-07-04)

Migraine is one of most disabling neurological disorders for which the genetic and molecular mechanisms are not fully resolved. This PhD thesis has focused on the functional characterization of two new missense mutations ...

Characterization of the in vivo functions of PrimPol, a novel TLS primase-polymerase

Stevanović, Irena (Date of defense: 2013-12-04)

We have identified PrimPol, a yet uncharacterized protein that can act in vitro as a low processivity polymerase able to bypasses thymine dimers in DNA. PrimPol localizes to both the nucleus and mitochondria. In order ...

Cutibacterium acnes strain improvement and establishment of skin microbiome sequencing technologies

Rozas Belmonte, Miquel (Date of defense: 2022-10-03)

Certain skin disorders are associated with skin microbiome dysbiosis, highlighting the importance of the microbiome in the maintenance of the skin's healthy state. Modulating the microbiome to reestablish its healthy state ...

Methodological preparation and characteritzation of the microbial ecology on the skin

Garcia i Garcerà, Marc (Date of defense: 2013-06-21)

The study of skin microbiota has always been focused from a clinical point of view. However, an ecological approach to the skin microbiota is impeded by different methodological limitations, including the high host/microbial ...