Browsing Universitat Pompeu Fabra by authors/directors "Tartaglia, Gian Gaetano"

Browsing Universitat Pompeu Fabra by authors/directors "Tartaglia, Gian Gaetano"

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  • Delli Ponti, Riccardo, 1987- (Date of defense: 16-01-2019)
    The secondary structure of an RNA molecule is fundamental for its function. However, structural conservation and the structure of RNA in vivo are still poorly understood. Data from recent high-throughput experiments can ...
  • Cid Samper, Fernando, 1991- (Date of defense: 27-01-2020)
    Ribonucleoprotein granules (RNP granules) are liquid-liquid phase separated complexes composed mainly by proteins and RNA. They are responsible of many processes involved in RNA regulation. Alterations in the dynamics ...
  • Armaos, Alexandros, 1989- (Date of defense: 23-01-2020)
    Despite what was previously considered, the role of RNA is not only to carry the genetic information from DNA to proteins. Indeed, RNA has proven to be implicated in more complex cellular processes. Recent evidence ...
  • Marchese, Domenica, 1986- (Date of defense: 14-11-2016)
    The role of RNA processing in the pathogenesis of neurodegenerative diseases is still poorly understood. α-synuclein (SNCA) is a presynaptic neuronal protein known as the major component of Lewy bodies, the pathological ...
  • Cirillo, Davide (Date of defense: 09-05-2016)
    The purpose of my doctoral studies has been the development of bioinformatics methods to quantitatively evaluate associations between proteins and nucleic acids (NAs). This thesis aims at providing insights into molecular ...
  • Agostini, Federico, 1985- (Date of defense: 16-06-2014)
    RNA-binding proteins (RBPs) control the fate of a multitude of coding and non-coding transcripts. Formation of ribonucleoprotein (RNP) complexes fine-tunes regulation of post-transcriptional events and influences gene ...
  • Lorenzo Gotor, Nieves, 1984- (Date of defense: 24-01-2020)
    Biomolecular condensates act as indispensable membrane-less organelles for intracellular organization and regulation of biochemical reactions. Proteins and RNAs are known to phase separate into condensates, however the ...
  • Dasti, Alessandro, 1988- (Date of defense: 22-01-2020)
    The molecular basis that sustain embryonic stem cell (ESCs) pluripotency and their differentiation in all the types of somatic cells is subject of intensive research. Recently, the potential involvement of RNA Binding ...
  • Klus, Petr, 1985- (Date of defense: 12-07-2016)
    The purpose of my doctoral studies was to develop an algorithm for large-scale analysis of protein sets. This thesis outlines the methodology and technical work performed as well as relevant biological cases involved in ...