Mostrando ítems 1-10 de 87
Villegas Mirón, Pablo (Fecha de defensa: 2021-07-19)
The evolutionary history of the human genome has been shaped by the selection of multiple elements in response to different environmental pressures. The analysis of regulatory adaptations and the ...
Ferrández Peral, Luis (Fecha de defensa: 2022-06-08)
The evolution of transcriptomes has been linked to the emergence of novel phenotypes. However, our knowledge on how isoform diversity has impacted recent human evolution is very limited. To fill this ...
Bou de Pieri, Francesc (Fecha de defensa: 2020-12-17)
Tot i que l’obesitat és clarament deguda a un desequilibri entre la ingesta d’energia i la despesa, i està molt associada a l’estil de vida, es considera una malaltia multifactorial amb una alta ...
Rodríguez Galindo, Miguel (Fecha de defensa: 2023-11-13)
Tumor progression is dominated by two evolutionary forces: first mutagenesis, which provides the heritable variability where, secondly, natural selection acts. The main challenge of cancer genomics is ...
Vicencio, Jeremy (Fecha de defensa: 2021-09-03)
In this thesis, I present an alternative, cloning-free method for the generation of endogenous fluorescent reporters in the nematode Caenorhabditis elegans. I demonstrate that Nested CRISPR is an efficient ...
Hinojosa Galisteo, Joan Carles (Fecha de defensa: 2021-06-23)
Butterflies are among the best studied animals, but despite the research efforts carried out during centuries, our knowledge on their diversity and on the mechanisms generating it is still incomplete. In ...
Dios Martínez, Toni de (Fecha de defensa: 2021-03-23)
Infectious diseases have affected humanity since its apparition in Africa 300,000 years ago. Demographic changes associated to the Neolithic transition, and ensuing population movements, have facilitated ...
Mixão, Verónica de Pinho (Fecha de defensa: 2020-10-20)
Candida species are among the most important fungal pathogens. Although Candida albicans is the most common cause of Candida infections, many other Candida species have emerged as pathogens. How ...
Dasti, Alessandro (Fecha de defensa: 2020-01-22)
The molecular basis that sustain embryonic stem cell (ESCs) pluripotency and their differentiation in all the types of somatic cells is subject of intensive research. Recently, the potential involvement ...
Maceda Porto, Iago (Fecha de defensa: 2021-04-28)
In this work we present a new whole genome sequencing dataset with samples gathered from the Spanish Eastern Pyrenees (SEP) with more than 40x coverage. We apply both classical and new methods to ...