Capella Gutiérrez, Salvador Jesús (Date of defense: 2012-11-16)
Phylogenomics is a biological discipline which can be understood as the intersection of the fields of genomics and evolution. Its main focuses are the analyses of genomes through the evolutionary lens ...
Manuel Montero, Marc de (Date of defense: 2018-12-11)
Els nostres parents més propers, els ximpanzés i els bonobos, tenen una història demogràfica complexa. En aquest estudi, hem analitzat els genomes sencers de 75 ximpanzés i bonobos nascuts en 10 països ...
Parra Farré, Genís (Date of defense: 2004-12-03)
El trabajo que aquí se presenta, estudia el reconocimiento de las señales que delimitan y definen los genes que codifican para proteínas, así como su aplicabilidad en los programas de predicción de ...
Serra Juhé, Clara (Date of defense: 2012-10-20)
Mechanisms underlying congenital malformations are largely unknown despite its high incidence, affecting 2-3% of liveborn infants. A broader knowledge about the causes of birth defects would provide ...
Nye, Jessica (Date of defense: 2018-12-17)
Although universal and unavoidable, aging does not occur in a uniform way. In this dissertation, we assessed the effects of early life exposure to pro-inflammatory risk factors (air pollution and obesity) ...
Prado Martínez, Javier (Date of defense: 2014-12-22)
Els grans simis són els nostres parents evolutius més propers i com a tals són la millor eina per entendre els nostres orígens més recents. Mitjançant la genòmica comparativa ara podem estudiar en ...
Gutiérrez Arumi, Armand (Date of defense: 2016-01-15)
Significant advances were performed in mapping and characterizing different types of structural variation in the human genome such as point mutations, insertions, deletions, etc. Nevertheless, there is ...
Arnedo Pac, Claudia Rosario (Date of defense: 2022-12-15)
Sequencing of cancer genomes reveals the story of mutational events shaping the distribution of somatic mutations across the nucleotide sequence. A particular pattern of such distribution, mutational ...
Prieto Barja, Pablo (Date of defense: 2017-01-12)
In this PhD I have used NGS technologies in different organisms and scenarios such as in ENCODE, comparing the conservation and evolution of long non-coding RNA sequences between human and mouse, using ...
Mechaly, Alejandro S. (Date of defense: 2011-06-27)
The recently discovered decapeptide kisspeptin and its G-protein coupled receptor form a signaling system expressed ubiquitously and are implicated in a variety of still poorly characterized functions. ...