Mostrando ítems 211-220 de 252
Jiménez Asins, Alba (Fecha de defensa: 2016-05-11)
Per tal d'estudiar la relació complexa entre l'estructura d'un circuit genètic i la seva funció, ens centrem en estudiar dues proprietas: la seva capacitat evolutiva i la seva multi-functionalitat. ...
Gallego Jiménez, Alicia (Fecha de defensa: 2016-11-14)
microRNAs are small non-coding RNAs with crucial roles in gene regulation and whose contribution to animal evolution has been largely demonstrated. In this thesis we explored some functional consequences ...
Morey Ramonell, Lluís (Fecha de defensa: 2008-02-01)
En mamíferos, así como en plantas, mutaciones en AND helicasas/ATPasas del la família SNF2, no solo afectan a la estructura de la cromatina, sino que también afectan al patrón global de la metilación ...
Lucas-Sánchez, Marcel (Fecha de defensa: 2023-09-18)
Since the origins of humankind, North Africa has been involved in many demographic events, leading to a heterogeneous cultural and genetic landscape. However, it is largely underrepresented in genetic ...
Di Giovanni, Francesca (Fecha de defensa: 2016-11-24)
Chromatin is not randomly organized inside the eukaryotic nucleus in interphase. In budding yeast gene expression of some specific loci is affected by their positioning in the nucleus. Replication ...
Burga Ramos, Alejandro Raúl (Fecha de defensa: 2012-07-20)
Genetically identical cells and organisms growing in homogenous environmental conditions can show significant phenotypic variation. Furthermore, mutations often have consequences that vary among individuals ...
Palacios Verdú, María Gabriela (Fecha de defensa: 2015-10-19)
Williams-Beuren syndrome is a neurocognitive disorder with multisystemic manifestations of variable expressivity caused by a 1.55-1.83 Mb at chromosomal band 7q11.23. In this thesis project we have ...
Gelabert Xirinachs, Pere (Fecha de defensa: 2018-12-14)
La malària és una malaltia infecciosa causada per diverses espècies de protozous del gènere Plasmodium, capaces d’infectar eritròcits humans. La malària és probablement la patologia infecciosa que ha ...
Aya Moreno, Francisco (Fecha de defensa: 2023-02-15)
Alternative splicing of BRAF mRNA can provide a resistance mechanism to BRAF and MEK inhibitors that has been described mostly in BRAF-mutant melanoma. The mechanisms underlying the production of a ...
Baeza Centurión, Pablo (Fecha de defensa: 2020-02-27)
Alternative pre-mRNA splicing is a regulated step in eukaryotic gene expression in which introns are removed from the transcript and exons are joined together to form a mature mRNA. To study the effects ...