Berniell Lee, Gemma (Date of defense: 2010-07-19)
La presente tesis, titulada “Genes, peoples and languages in Central Africa”, examina los patrones de diversidad genética en poblaciones del oeste de Africa central, más específicamente, poblaciones ...
Mugianesi, Francesca (Date of defense: 2022-06-02)
Gene expression, epigenetic states and topological conformation are three fundamental aspects of genome organization that are tightly regulated in space and time. Epigenetic states, protein occupancy ...
Balart i García, Pau (Date of defense: 2023-02-24)
Under very specific pressures, evolution turns extremely convergent, to the extent that distantly-related organisms show highly similar morphological, physiological and behavioral adaptations. Life into ...
Martínez Fernández, Carmen (Date of defense: 2021-03-12)
Model organisms and gene-editing strategies are fundamental to address a variety of scientific questions from basic science to biomedical research. Here, we reinforced the use of two powerful tools, ...
Sikora, Martin (Date of defense: 2010-06-04)
Una de les forces selectives més fortes que han afectat a les poblacions humanes en la història més recent és el paràsit de la malària: Plasmodium falciparum, que és la causa de varis exemples d'adaptació ...
Morcillo Suárez, Carlos (Date of defense: 2011-12-19)
New approaches are needed to manage and analyze the enormous quantity of biological data generated by modern technologies. Existing solutions are often fragmented and uncoordinated and, thus, they require ...
Roca-Umbert Würth, Ana (Date of defense: 2021-12-22)
Zinc is an essential micronutrient involved in many different biological processes. Zinc homeostasis is mainly regulated by 24 zinc transporters coded by the Zinc Transporter Genes (ZTGs). Notably, zinc ...
Plass Pórtulas, Mireya (Date of defense: 2011-07-12)
L’splicing és el mecanisme pel qual els introns són eliminats del pre-mRNA per generar un trànscrit madur. Aquest procés és dut a terme per un complex macromolecular anomenat spliceosoma i requereix el ...
Mas Martín, Glòria (Date of defense: 2007-07-20)
En la levadura S. cerevisiae, un incremento de la osmolaridad extracelular activa la vía de Hog1, lo que produce una compleja respuesta adaptativa. Entre las respuestas adaptativas que Hog1 coordina, ...
Ferreiro Neira, Isabel (Date of defense: 2011-10-07)
Regulation of transcription by Stress Activated Protein Kinases (SAPKs) is an essential aspect for adaptation to extracellular stimuli. In mammals, the activation of the p38 SAPK results in the regulation ...