Mularoni, Loris (Date of defense: 2009-07-28)
Tandem amino acid repeats, also known as homopolimeric tract or homopeptides, are very common features of eukaryotic genomes and are present in nearly one-fifth of human encoded proteins. These structures ...
Khatri, Safia (Date of defense: 2009-03-23)
En els darrers anys s'ha produït un gran avenç en l'enteniment dels mecanismes implicats en la inducció de la placoda òtica. Tanmateix, poc es coneix encara de com s'estableix un domini amb competència ...
Vali Pour Jamnani, Mischan (Date of defense: 2022-06-02)
Somatic mutations are an inevitable component of ageing and the most important cause of cancer. The rates and types of somatic mutation vary across individuals, but relatively few inherited influences ...
Breschi, Alessandra (Date of defense: 2016-11-28)
Mice are the premier model organisms to study human biology and disease, but there is still debate about the extent to which molecular mechanisms are conserved between human and mouse. With the advance ...
Soldevila Trepat, Marta (Date of defense: 2005-06-20)
En el gen de la proteïna priònica, o PRNP, hem observat que el particular patró de variació que hem trobat basant-nos en dades de seqüenciació en humans es deu a selecció positiva, i que el mètode ...
Marquès i Bonet, Tomàs (Date of defense: 2007-01-15)
The main objectives of this work are:<br/>a) To test the predictions of suppressed-recombination chromosomal speciation models on two different lineages of mammals: rodents and rimates. Suppressed-recombination ...
Corrales Berjano, Marc (Date of defense: 2018-01-19)
This thesis reports the study of chromatin composition and conformation on the expression of integrated reporters at thousands of genomic locations in the Drosophila genome. We have adapted and improved ...
Crowley, Valerie Margarita (Date of defense: 2011-11-02)
Clonally variant gene expression (CVGE) is a common survival strategy used by many pathogens, including the malaria parasite Plasmodium falciparum. Among the genes that show CVGE are several members of ...
Soler Vila, Paula (Date of defense: 2019-12-09)
High-throughput Chromosome Conformation Capture (3C) techniques have provided a comprehensive overview of the genome architecture. Hi-C, a derivative of 3C, has become a reference technique to study the ...
Nadal Ribelles, Mariona (Date of defense: 2013-11-25)
A fundamental property of living cells is the ability to sense and robustly respond to fluctuations in their environment. In budding yeast (Saccharomyces cerevisiae) changes in extracellular osmolarity ...