Povolotskaya, Inna (Date of defense: 2015-02-16)
Se ha predicho teóreticamente que la epistasis, es decir, las interacciones genéticas entre diferentes mutaciones, cumple un rol sustancial en procesos evolutivos, tales como la emergencia de la ...
Naranjo Ortiz, Miguel Ángel (Date of defense: 2019-01-18)
Non-vertical genomic events, which include horizontal gene transfer (HGT) and hybridization, are widely studied evolutionary processes in certain groups. HGT is particularly well known for prokaryotic ...
Miravet Verde, Samuel (Date of defense: 2021-05-14)
Small proteins (SEPs; <100aa) are involved in essential processes such as cell homeostasis, signalling, or metabolism. However, they have been overlooked because of computational and experimental ...
Galan Martínez, Silvia (Date of defense: 2020-11-17)
El desenvolupament de tècniques experimentals basades en la captura de la conformació genòmica (3C), han aportat informació rellevant sobre l’estructura del genoma. En particular el Hi-C, un derivat del ...
Montaner Domènech, Anna (Date of defense: 2019-11-11)
discovery of cell-free DNA (cfDNA) in blood and the advent of massive parallel sequencing technologies has revolutionized the prenatal screening field by providing a better risk assessment of fetal ...
Batlle Masó, Laura (Date of defense: 2021-03-02)
Des de l’aparició de les eines de seqüenciació genòmica, el genoma humà s’ha explorat per a trobar variants causants de malaltia. Les malalties són diverses, i conseqüentment, també ho són les seves ...
Mondal, Mayukh (Date of defense: 2016-11-21)
Human genome project published their first human whole genome sequence on 2001 at the cost of billions of dollars. Since, the cost of sequencing is decreasing faster than Moore’s law. Now, we not only ...
Schütz, Martin Maximilian (Date of defense: 2011-07-01)
Mitosis is the essential process during which a cell divides into two viable daughter cells. To allow a faithful segregation of the chromosomes into each daughter, the cell forms the bipolar spindle. ...
Radó i Trilla, Núria (Date of defense: 2013-05-03)
In this thesis we aimed to study evolutionary implications of low-complexity regions, protein sequences of very simple amino acid composition. Its uncontrolled expansion causes several human diseases, ...
García Fernández, Carla (Date of defense: 2021-12-16)
Europe is a rich combination of diversities, cultures, and populations. Roma is the largest ethnic minority of Europe, accounting for an estimated >10 million citizens, although no official census is ...