Rodríguez Pérez, Juan Antonio (Date of defense: 2017-01-24)
Old age comes coupled with frailty and disease and, thus, the ageing of the World’s population have spurred the interest on the causes and mechanisms of senescence. Senescence has long been a mystery, ...
Ferrando-Bernal, Manuel (Date of defense: 2021-07-09)
The aim of this thesis is to apply Identity by Descent (IBD) methodology to identify ancestry connections among individuals from genetically similar populations. Recombination events diminish the ...
Shaw, Daniel (Date of defense: 2019-12-13)
Understanding what constitutes a true Minimal Cell is a key challenge in synthetic biology. In this work, we present two new tools to aid in this endeavour. i) A novel methodology for minimising the ...
Hernandez Alias, Xavier (Date of defense: 2023-02-23)
Malgrat teixits diferents presenten diferències en l'ús de codons i en els repertoris d'anticodons dels ARNt, el coneixement sobre la co-adaptació entre codó-anticodó en eucariotes multicel·lulars és ...
Ledda, Alice (Date of defense: 2011-05-06)
Els microsat el lits s on seq u encies d'ADN formades per repeticions en t andem de motius curts. Les curtes seq u encies repetides en t andem s on ubiq ues en els genomes dels eucariotes, tant en les ...
Renom, Pere (Date of defense: 2023-02-22)
According to estimates, over the 3.5 billion years that have elapsed since the appearance of life, the Earth has been inhabited by some 4 billion different species, of which 99.99% have already become ...
Dall'Olio, Giovanni Marco (Date of defense: 2013-10-28)
In this thesis we developed two approaches to study positive selection and genetic adaptation in the human genome. Both approaches are based on applications of network theory. In the first approach, ...
Mandage, Rajendra (Date of defense: 2018-01-12)
The EBV has been linked to multiple human disease phenotypes and has been associated with cancers and other infections. Recently single gene analysis and genome-wide analysis studies have been exploited ...
Carnero-Montoro, Elena (Date of defense: 2013-10-25)
The genetic basis of phenotypes that have contributed to the adaptation of species and organisms to new environments is a central question in evolutionary genetics. The recent accumulation of genetic ...
Ballana Guix, Ester (Date of defense: 2007-05-04)
La seqüenciació del genoma humà ha marcat una fita important en la història de la biologia. Com a conseqüència, la genètica i la genòmica han experimentat un progrés enorme. Això ha permès un millor ...