Hernando Herráez, Irene (Date of defense: 2015-07-24)
DNA methylation is a crucial epigenetic modification involved in numerous biological processes. However, despite its functional importance, the evolutionary history of this modification and the mechanisms ...
Verd Fernández, Berta (Date of defense: 2016-01-21)
During insect development segments either form sequentially (short-germband) or simultaneously (long-germband) . The gap genes comprise the first zygotic regulatory layer of the segmentation gene ...
Marmi Plana, Josep Maria (Date of defense: 2006-06-23)
Els treballs realitzats en aquesta tesi tenen com objectius l'aplicació de la sistemàtica molecular i la filogeografia per resoldre relacions filogenètiques, clarificar la taxonomia i descriure la ...
Kremsky, Isaac Jacob (Date of defense: 2015-07-14)
Proteins that bind to DNA or RNA are both known to influence alternative splicing. However, there has not been so far a systematic experimental exploration of the relationship between these factors ...
Povolotskaya, Inna (Date of defense: 2015-02-16)
Se ha predicho teóreticamente que la epistasis, es decir, las interacciones genéticas entre diferentes mutaciones, cumple un rol sustancial en procesos evolutivos, tales como la emergencia de la ...
Naranjo Ortiz, Miguel Ángel (Date of defense: 2019-01-18)
Non-vertical genomic events, which include horizontal gene transfer (HGT) and hybridization, are widely studied evolutionary processes in certain groups. HGT is particularly well known for prokaryotic ...
Miravet Verde, Samuel (Date of defense: 2021-05-14)
Small proteins (SEPs; <100aa) are involved in essential processes such as cell homeostasis, signalling, or metabolism. However, they have been overlooked because of computational and experimental ...
Galan Martínez, Silvia (Date of defense: 2020-11-17)
El desenvolupament de tècniques experimentals basades en la captura de la conformació genòmica (3C), han aportat informació rellevant sobre l’estructura del genoma. En particular el Hi-C, un derivat del ...
Montaner Domènech, Anna (Date of defense: 2019-11-11)
discovery of cell-free DNA (cfDNA) in blood and the advent of massive parallel sequencing technologies has revolutionized the prenatal screening field by providing a better risk assessment of fetal ...
Martínez Arias, Rosa (Date of defense: 2001-03-12)
Hemos analizado la variabilidad genética de una zona no codificante autosómica, el pseudogén homólogo al gen de la glucocerebrosidasa (psGBA). <br/>Parte del análisis se ha realizado desde la perspectiva ...