Esteller Cucala, Paula (Date of defense: 2023-04-18)
Changes in the epigenetic regulation of gene expression have important implications for evolution. However, the study of these changes (i) has not been consistently assessed across closely related ...
Pant, Devesh Chandra (Date of defense: 2018-10-05)
In spite of recent advances in understanding the genetic bases of leukodystrophies, a large number of clinical cases remain unexplained, suggesting that many leukodystrophy-associated genes have yet to ...
Fontseré Alemany, Clàudia (Date of defense: 2020-12-17)
Wild chimpanzee populations are considered to be under threat of extinction due to the damaging consequences of human impact into their natural habitat and illegal trade. Conservation genomics is an ...
Rodríguez Pérez, Juan Antonio (Date of defense: 2017-01-24)
Old age comes coupled with frailty and disease and, thus, the ageing of the World’s population have spurred the interest on the causes and mechanisms of senescence. Senescence has long been a mystery, ...
Ferrando-Bernal, Manuel (Date of defense: 2021-07-09)
The aim of this thesis is to apply Identity by Descent (IBD) methodology to identify ancestry connections among individuals from genetically similar populations. Recombination events diminish the ...
Shaw, Daniel (Date of defense: 2019-12-13)
Understanding what constitutes a true Minimal Cell is a key challenge in synthetic biology. In this work, we present two new tools to aid in this endeavour. i) A novel methodology for minimising the ...
Hernandez Alias, Xavier (Date of defense: 2023-02-23)
Malgrat teixits diferents presenten diferències en l'ús de codons i en els repertoris d'anticodons dels ARNt, el coneixement sobre la co-adaptació entre codó-anticodó en eucariotes multicel·lulars és ...
Ledda, Alice (Date of defense: 2011-05-06)
Els microsat el lits s on seq u encies d'ADN formades per repeticions en t andem de motius curts. Les curtes seq u encies repetides en t andem s on ubiq ues en els genomes dels eucariotes, tant en les ...
Renom, Pere (Date of defense: 2023-02-22)
According to estimates, over the 3.5 billion years that have elapsed since the appearance of life, the Earth has been inhabited by some 4 billion different species, of which 99.99% have already become ...
Lucas, Morghan C. (Date of defense: 2023-04-24)
The aim of this thesis is to delve into sperm RNA dynamics during maturation and paternal inheritance. To obtain an integrative multi-omics view of sperm RNA during these processes, I turned to the new ...