Hernando Herráez, Irene (Date of defense: 2015-07-24)
DNA methylation is a crucial epigenetic modification involved in numerous biological processes. However, despite its functional importance, the evolutionary history of this modification and the mechanisms ...
Homs Raubert, Aïda (Date of defense: 2015-09-15)
The aetiology of autism spectrum disorders (ASD), a group of neurodevelopmental conditions with early onset, characterized by social and communication impairment and restricted interests, is unknown in ...
Herranz Martín, Nicolás (Date of defense: 2011-09-23)
The epithelial to mesenchymal transition (EMT) is a highly conserved cellular program that allows well-‐differentiated epithelial cells to convert to motile mesenchymal cells. ...
Missarova, Alsu (Date of defense: 2018-04-09)
Isogenic cells exhibit a large degree of cell-to-cell heterogeneity in proliferation, with a subpopulation of cells growing at a substantially lower rate. We conducted a high throughput microscopy screen ...
Jené i Sanz, Alba (Date of defense: 2013-04-29)
El càncer ha estat tradicionalment considerat una malaltia fonamentalment genètica, però recentment s'està fent palès que la desregulació de mecanismes epigenètics contribueix en gran manera ...
Domínguez Rodríguez, Diana (Date of defense: 2021-05-04)
La metàstasis és responsable del 90% de les morts per càncer, demostrant l’existent manca de coneixement en relació als seus mecanismes moleculars. Investigacions anteriors del nostre laboratori han ...