Oñate Monje, Lorena de (Date of defense: 2015-11-23)
Probably, the gain in organ complexity and cell function has led to a decrease in healing capacities in the adult mammalian heart. In an effort to generate new venues for the generation of functional ...
Sáez Borderias, Andrea (Date of defense: 2009-02-20)
This work is centered on the study of the NKG2 C-type lectin-like receptors on NK and CD4+T cells. We provide evidence supporting that CD4+T cells specific for Human Cytomegalovirus (HCMV) may express ...
Iturbide Martínez de Albéniz, Ane (Date of defense: 2016-03-15)
Protein function is often regulated and controlled by posttranslational modifications, such as oxidation. Although oxidation has been mainly considered to be uncontrolled and nonenzymatic, many enzymatic ...
Scrofani, Jacopo (Date of defense: 2014-10-10)
During mitosis, spindle assembly involves different sources of microtubules including centrosomes and chromosomes. While the role of centrosomes has been extensively studied, we still do not fully ...
Cortés Albarracín, Paola Andrea (Date of defense: 2019-12-02)
Mouse embryonic stem cells (ESCs) require extracellular signals to induce the expression of intrinsic core pluripotency factors: Oct4, Sox2 and Nanog, known as the OSN triad. Notably, the Wnt/β-catenin ...
Adrover Nadal, Miguel Angel (Date of defense: 2009-09-18)
Control of cell cycle by Stress Activated Protein Kinases (SAPKs) is an essential aspect for adaptation to extracellular stimuli. In Saccharomyces cerevisiae, the activation of the Hog1 SAPK, results ...
Zaurín Quer, Roser (Date of defense: 2009-07-16)
Evidències recents han remarcat la importància del paper de l'estructura de la cromatina i el posicionament de nucleosomes en processos cel·lulars bàsics com és la regulació de la transcripció gènica. ...
Di Tullio, Alessandro (Date of defense: 2012-07-13)
Our earlier work has shown that pre-B cells can be converted into macrophages by the transcription factor C/EBPα at very high frequencies and also that a clonal pre-B cell line with an inducible form ...
Guerra Badell, Joana (Date of defense: 2016-10-13)
Adult skeletal muscle has a remarkable capacity of self-repairing after damage. The cellular communication processes and mediator molecules in the regenerative microenvironment that control muscle stem ...
Gonzàlez Busqué, Núria (Date of defense: 2017-09-18)
Snail1 transcription factor is the key inducer of epithelial-to-mesenchymal transition (EMT). Here, we describe a novel role for Snail1 on the regulation of telomere integrity and transcription as well ...