Ara mostrant els elements 1-10 de 59
Martí Solano, Maria (Data de defensa: 2015-02-10)
La caracterització de diversos fàrmacs capaços d’unir-se a receptors associats a proteïnes G (GPCR)s ha revelat que els seus mecanismes d’acció no eren tan simples com es creia. Primer, l’anàlisi de la ...
Księżopolska, Ewa (Data de defensa: 2021-07-05)
This project was set out to broaden our knowledge of the processes driving the emergence of antifungal drug resistance in an opportunistic yeast pathogen Candida glabrata. More precisely, we sought to ...
Almeida Cotrim, Bruno (Data de defensa: 2011-01-10)
Obesity constitutes a problem whose manifestations have consequences in almost every field of the medicine and nowadays there is a lack of pharmacological therapy alternatives for its long term ...
An, Weiteng (Data de defensa: 2021-04-14)
Peptide-based vaccines have raised as an attractive alternative strategy to overcome many of the limitations of conventional vaccines. Some drawbacks for an optimal immune response in vivo are, a poor ...
Gallo, María (Data de defensa: 2021-07-22)
This thesis focuses on one of the biggest challenges facing drug discovery field: the efficient targeted delivery of therapeutic compounds, and how cell-penetrating peptides (CPPs) acting as drug delivery ...
Falaguera Mata, Maria José (Data de defensa: 2022-04-26)
Systems pharmacology is the discipline that studies the so-called ‘pharmacological space’ with a holistic and network-based perspective. Its challenge is to shed light on the astonishingly sophisticated ...
Such Sanmartin, Gerard (Data de defensa: 2010-01-28)
Human growth hormone (GH) participates in human longitudinal growth, lipid and carbohydrate metabolism, and comprises a remarkably number of proteins with similar sequences, generated either genetically ...
Pinto Gil, Kevin (Data de defensa: 2020-01-31)
Despite the investment of vast amounts of money over the last decades, drug discovery and development remains an inefficient process, which can be stopped at different steps, leading to the loss of ...
Szabó, Viktória (Data de defensa: 2019-03-13)
The demographic shift toward an aging population is increasing the burden of public health. On average, a person of 70 years can combine the intake of up to seven medications. The administration of ...
Vila Rodríguez, Javier (Data de defensa: 2016-11-25)
Introducción: Con el fin de mejorar los métodos de evaluación de la exposición a campos electromagnéticos, desarrollamos un nuevo método basado en fuentes de exposición en lugar de códigos de ocupación. ...