Universitat Pompeu Fabra
Mostrando ítems 1-10 de 321
The evolutionary success of insects was particularly shaped by the innovation of the metamorphosis, especially by the transition from hemimetaboly to holometaboly. The mechanisms underlying this ...
We have monitored the transcriptome and the epigenome of human pre-B cells transdifferentiating into macrophages. Analysis of these data provides a general framework to understand the relationship between ...
Widespread transcription in mammals revealed unexpected discovery of non-coding elements like long noncoding RNAs (lncRNAs) and repetitive elements. First, lncRNAs were previously identified in limited ...
Germline copy-number variants (CNVs), as well as somatic copy-number alterations (CNAs), play an important role in many phenotypic traits, including genetic diseases and cancer. Next Generation Sequencing ...
L’estudi de la variació estructural complementa l’estudi de la variació de seqüència per revelar les complexitats de la variació fenotípica. Els gossos són l’espècie domesticada amb més variació fenotípica ...
Most of the Native American populations that lived in nowadays Eastern Brazil when the Europeans established in the area in the 16th century do not exist anymore. The colonization of Brazil implied huge ...
Mesoamerica is one of the main centers of New World civilization. It represents today a large geographical area exhibiting one of the highest genetic, cultural, and archeological diversity in the Americas. ...
Identification of signatures of positive selection has long been a major issue for understanding the unique features of any given species. However, only a fraction of human genes have been interrogated. ...
En el gen de la proteïna priònica, o PRNP, hem observat que el particular patró de variació que hem trobat basant-nos en dades de seqüenciació en humans es deu a selecció positiva, i que el mètode ...
DNA damage is an ongoing threat to both the ability of the cell to faithfully transmit genetic information to its offspring as well as to its own survival. In order to maintain genomic integrity, ...
