Sodaei, Reza (Date of defense: 2020-05-22)
How do genomes generate different tissues, behaviours, individuals or species? We try to identify parts of the human transcriptome that we found only in a tissue. Then, we focus on inter-individual ...
Mantica, Federica (Date of defense: 2023-05-11)
Regulated Gene Expression (rGE) and Alternative Splicing (rAS) are two of the main mechanisms contributing to tissue-phenotypic diversity within and between species. In this thesis, we aim at characterizing ...
Wyatt, Christopher Douglas Robert (Date of defense: 2019-06-19)
The transition from maternal to embryonic control is a crucial time in an organism’s life cycle, with an overhaul of the epigenetic marks, targeted mRNA degradation and the initiation of transcription. ...