Ara mostrant els elements 1-10 de 21
Espeso Gil, Sergio (Data de defensa: 2016-12-05)
El reguloma està constituït per un sistema complex de factors que controlen el fenotip molecular de la cèl·lula, que al seu torn està influenciada pel medi ambient. Qualsevol pertorbació pot desencadenar ...
Santesmasses Ruiz, Didac (Data de defensa: 2016-12-12)
La selenocïsteina és coneguda com a l'aminoàcid 21. Les selenoproteïnes incorporen selenocïsteina en resposta a codons UGA específics mitjançant un mecanisme de recodificació, el qual és present en els ...
Hartasánchez Frenk, Diego Andrés (Data de defensa: 2016-11-22)
Les regions duplicades del genoma, com ara les duplicacions de segments (SDs), són una característica comuna dels genomes eucariotes i han estat associades a canvis fenotípics. Donada la seva rellevància ...
Valles Ibáñez, Guillem de (Data de defensa: 2016-11-16)
Human genomes have been found to harbor an unexpected number of ~100 loss-of-function (LoF) variants, with ~20 of them in an homozygous state, in most cases without a visible effect despite its potential ...
Sinha, Roshani (Data de defensa: 2016-12-16)
Rearrangements involving the mixed lineage leukemia gene (MLL) are found in majority of human infant leukemias (>60% of ALLs, 35% of AMLs) and are associated with dismal prognosis of these patients. ...
Gutiérrez Arumi, Armand (Data de defensa: 2016-01-15)
Significant advances were performed in mapping and characterizing different types of structural variation in the human genome such as point mutations, insertions, deletions, etc. Nevertheless, there is ...
Chatzou, Maria (Data de defensa: 2016-11-07)
One of the main and most recent challenges of modern biology is to keep-up with growing amount of biological data coming from next generation sequencing technologies. Keeping up with the growing volumes ...
Spataro, Nino (Data de defensa: 2016-10-26)
From Darwin’s “On the Origin of Species”, many years elapsed before human diseases were considered in an evolutionary framework. Besides theoretical and empirical advances, we are far from the complete ...
Olalde Marquínez, Íñigo (Data de defensa: 2016-07-22)
The general objective of this thesis is to use ancient genomic data to study the European prehistory. Thanks to the latest advances in DNA sequencing technologies, the field of ancient DNA has suffered ...
Carvalho, Tiago Loureiro de (Data de defensa: 2016-01-21)
Genetic variation in humans and the great apes has been amply explored using a wide variety of markers, among them tandem repeats (TRs). Because of the nature of TRs, highly variable in length due to ...