Piñero González, Janet (Date of defense: 2015-12-17)
In the last two decades, the volume and variety of biomedical data has dramatically increased. The data is heterogeneous and scattered across many resources. This produces bottlenecks in the analysis ...
Czerniak, Natalia Dorotea (Date of defense: 2015-06-23)
Morphogenesis creates a plethora of complex shapes in plants and animals. We devote this work to the study of Drosophila head involution (HI), a late embryogenetic process, which involves complete ...
Kłosin, Adam (Date of defense: 2015-11-09)
Desde Darwin y Lamarck, a los biólogos les ha intrigado la posibilidad de que rasgos adquiridos debido al ambiente pudieran ser heredados. Se han descrito muchos ejemplos de este tipo debidos a ...
Ertl, Iris Elisabeth (Date of defense: 2015-02-20)
El complexos SWI/SNF són remodeladors de cromatina dependents d’ATP que es troben altament conservats al llarg de l’evolució. Aquests complexos poden regular l’accessibilitat a una zona genòmica alterant ...
Villanueva Cañas, José Luis (Date of defense: 2015-11-20)
Although the genome sequencing revolution is still in its infancy, we must acknowledge it as the major driver of biology since the beginning of the 21st century. The availability of a large collection ...
Pybus Oliveras, Marc (Date of defense: 2015-09-28)
Detecting positive selection in genomic regions is a recurrent topic in human population genetics studies. Over the years, many positive selection tests have been implemented to highlight specific genomic ...
Trussart, Marie (Date of defense: 2015-10-30)
Des de l’aparició de les tecnologies de seqüenciació d’alt rendiment, els conjunts de dades biològiques han esdevingut cada cop més grans i complexes, la qual cosa els fa pràcticament impossibles ...
Szóstak, Emilia (Date of defense: 2015-12-10)
Unequal dosage of X-linked genes between males (XY) and females (XX) is balanced by dosage compensation mechanisms. In Drosophila melanogaster, the dosage compensation complex specifically induces a ...
Elshaer, Nashwa Ahmed Ali Mohammed (Date of defense: 2015-03-16)
The present work aims at establishing the first bases for studying the insect oocyte polarity in a phylogenetically basal species, the cockroach Blattella germanica. Our approach was to choose some genes ...
Meer, Margarita V. (Date of defense: 2015-12-09)
Fitness landscape is a concept, which describes the dependence of phenotype on genotype. It was proposed almost a hundred years ago but only recent burst of technologies finally allowed exploring it. ...