Sansó Martínez, Miriam (Date of defense: 2010-07-02)
In Schizosaccharomyces pombe, the MAPK pathway Sty1 is activated upon several stress situations, like osmotic and oxidative stress, stationary phase, UV radiation or heat shock. Since the modulation ...
Fraile Beneitez, Rodrigo (Date of defense: 2021-07-23)
Eukaryotic DNA is condensed inside the nucleus, compacted into chromatin. The structure of chromatin is dynamic, and its accessibility to cellular machinery can be altered depending on the level of ...
Calvo Arnedo, María Isabel (Date of defense: 2012-12-21)
En el laboratorio se utiliza como sistema modelo la levadura Schizosaccaromyces pombe para poder estudiar la respuesta a estrés oxidativo. Las dos rutas principales de respuesta a estrés oxidativo son ...
Paulo Mirasol, Esther (Date of defense: 2014-12-19)
Reactive oxygen species (ROS) are a variety of molecules derived from molecular oxygen during different metabolic processes. ROS can react with different cellular components resulting in lipid peroxidation, ...
García Santamarina, Sarela (Date of defense: 2013-06-14)
Oxidation of specific cysteines in proteins by hydrogen peroxide (H2O2) is a cellular mechanism that triggers signalling pathways, such as the antioxidant responses in microbial systems. However, H2O2 ...
Marte, Luis (Date of defense: 2020-01-31)
Proteostasis is the proper homeostasis of the concentration and the molecular structure of the proteins, which preserves the integrity of the proteome. Proteo-stasis is constantly challenged by intrinsic ...
Domènech Guil, Alba (Date of defense: 2018-03-02)
Schizosaccharomyces pombe, com tots els organismes aeròbics, requereix l’oxigen per viure i té que lidiar amb la conseqüent toxicitat associada dels productes derivats de l’oxigen. Per mantenir l’ambient ...