Universitat Pompeu Fabra: Envíos recientes
Mostrando ítems 21-40 de 3434
La independencia judicial y el desafio populista
La presente tesis doctoral aborda en qué forma el auge del populismo ha socavado la independencia de los tribunales, un elemento esencial para el Estado de Derecho. A pesar de su ambigüedad, el populismo ha emergido en ...
Culpabilidad sin posibilidad de obrar en contrario: fundamentos teóricos de la imputación personal
El estudio que se presenta a continuación explora las bases teóricas de la imputación personal del injusto, centrándose en la relación entre el concepto de libertad individual y la responsabilidad penal. Se somete a ...
Adopción y familia de origen: vínculos personales y familiares de las personas adoptadas
Las personas adoptadas disponen de vínculos personales con dos estructuras familiares, la de origen y la adoptiva, que deben ser atendidos por un sistema adoptivo que busca proporcionar el bienestar y la protección de los ...
International Protection: A Novel Approach to an Autonomous Legal Concept that protects Non-Nationals at Risk of Harm
The present doctoral thesis unveils the contemporary autonomous meaning of ‘international protection’ as an umbrella concept suited to cover all situations in which a state must grant a non-national the right to stay on ...
Political Representation of Future Generations: Justice, Legitimacy, and Institutional Design
This thesis establishes essential criteria for effectively and legitimately representing future generations within democratic systems, particularly in the context of environmental crises, such as climate change, ...
Charting the alternative splicing vulnerabilities of cancer
Cancer co-opts alternative splicing to select isoforms that promote disease initiation, progression, and persistence. Drugs targeting either cancer driver splicing factors or specific splicing events can hamper the disease. ...
Attributing heat-related mortality to climate change
Climate change significantly exacerbates public health risks, particularly heat-related mortality. This PhD thesis examines the impact of human-induced climate change on heat-related deaths in Europe, focusing on regional ...
Evaluación del valor pronóstico de la ecografía pulmonar en el infarto agudo de miocardio con elevación del ST (LUS-AMI)
La insuficiencia cardíaca (IC) es un factor pronóstico crucial en pacientes con infarto agudo de miocardio con elevación del ST (IAMEST). La ecografía pulmonar es una técnica ampliamente estudiada en pacientes con insuficiencia ...
New insights into the clinical utility of LMO2
This thesis offers novel information on the clinical utility of LMO2, shown in three different studies. In the first one, we generated a round-robin testing validating the interobserver and interlaboratory reproducibility ...
A novel computational framework for identifying epileptogenic networks based on functional connectivity changes
Esta tesis se centra en mejorar la precisión de los objetivos quirúrgicos en pacientes con epilepsia resistente a los fármacos. Las redes cerebrales epileptogénicas exhiben cambios significativos en la conectividad durante ...
Dirección algorítmica en la relación laboral: derechos de información y consulta
El objetivo de esta tesis es analizar, desde un punto de vista interdisciplinar y transversal, los derechos de información y consulta derivados de la implantación de sistemas de dirección algorítmica en el ámbito laboral. ...
Beyond the Member State: Subnational Infringements of European Environmental Directives
This dissertation examines the extent to which subnational authorities comply with European environmental directives. Problematic implementation of EU environmental legislation is well-known, but continued noncompliance ...
Worlds apart: The impact of (in)congruence on electoral behaviour: When voters and parties do not align
This thesis provides a comprehensive analysis of the impact of ideological incongruence between voters and political parties on electoral behaviour in European democracies. It introduces a novel approach to measuring the ...
El impacto de la vivienda cooperativa en la salud de las personas: compartir para vivir
El objetivo principal de esta tesis ha sido profundizar y ampliar en el conocimiento sobre la vivienda cooperativa y su impacto en la salud de las personas. Para alcanzar este objetivo, se han diseñado y llevado a cabo ...
Evaluation of topoisomers of snake venom-derived peptides as potential antimicrobial and antitumor agents
This thesis reports an investigation of the effect of topoisomeric modification on the activity of two peptides: crotalicidin (Ctn), a cathelicidin from the venom of a South American rattlesnake, and Ctn[15-34], a Ctn ...
Evolutionary dynamics of cancer drug resistance and prediction of tumor modes of growth
Cancer remains a significant challenge in healthcare and is a leading concern worldwide. Despite advances in cancer therapy and the identification of numerous actionable events, relapse and drug resistance continue to ...
Beyond Boundaries: Leveraging Visual Data for Advancements in Social Science Research
This thesis focuses on visual data collected in the frame of online surveys, examining the main challenges and implications of collecting and analyzing these new data types. Given the relatively unexplored implementation ...
Access of Migrant Women to Labor Market in Germany: Exploring the Barriers, Opportunities, and Experiences
This dissertation is a mixed-method research project divided into three articles, each of which focuses on a different aspect of labor market integration for migrant women. The first chapter analyzes the experiences ...
Novel experimental strategies to characterize the genomic architecture of monogenic autoinflammatory diseases: from characterization of aberrant mRNA transcripts to elucidation of the role of post-zygotic variants in desease pathogenesis
Developments in sequencing technologies over the last decade have revolutionized the ability to identify the genetic mechanisms underlying rare autoinflammatory diseases (AIDs), enabling improved characterization and ...
The molecular mechanism of spindle pole focusing: NuMA as a dynein adaptor and microtubule minus end regulator
This project investigates the molecular mechanisms underlying chromosome segregation during eukaryotic cell division. Specifically, it explores the role of the motor protein cytoplasmic dynein 1 in maintaining metaphase ...
