Ara mostrant els elements 142-161 de 234
Errea Lorenzo, Oihana (Data de defensa: 2014-09-23)
La Esclerosis Múltiple (EM) afecta preferentemente a la conectividad cerebral lesionando los axones de forma irreversible, siendo esta lesión la principal causa de la discapacidad permanente de los pacientes. El daño axonal ...
Rica Lázaro, Lorenzo de la (Data de defensa: 2014-02-14)
La presente tesis doctoral se ha centrado en investigar los procesos de desregulación en la metilación del DNA y de microRNAs en dos tipos celulares implicados en la patogenia de la artritis reumatoide, cuya función se ...
Gómez Bardallo, Raquel (Data de defensa: 2023-03-10)
[spa] La lesión por isquemia-reperfusión (IR) es la mayor causa de pérdida y disfunción de tejidos y órganos en trasplantes clínicos, como es el trasplante hepático. Durante la isquemia, la carencia de oxígeno provoca ...
Dyson Coral, Silvia (Data de defensa: 2021-12-14)
Topoisomerase II often produces DNA knots and catenates when its DNA strand passage activity equilibrates the topology of intracellular DNA. However, these DNA entanglements are detrimental for the normal development of ...
Bartomeu i Galan, Anna (Data de defensa: 2024-01-29)
[eng] Cytoplasmic Polyadenylation Element Binding proteins (CPEBs) are a family of RNA-binding proteins that regulate cytoplasmic changes in poly(A) tail lengh and therefore mRNA-specific stability and translation. Since ...
Calvo Serrano, Isabel (Data de defensa: 2024-02-16)
[eng] Our understanding of the transcriptional control of cellular identity is rapidly emerging. Mediator complex enriches at active enhancers, forms a protein bridge to target genes, and recruits RNA Polymerase II ...
Tecchio, Samuele (Data de defensa: 2013-02-14)
The Mediterranean Sea can be considered an excellent natural laboratory for benthic ecologists, due to its peculiar environmental conditions, its broad-scale gradients, and its deep-sea fauna. Primary production levels in ...
Denis López, Carmen (Data de defensa: 2021-11-05)
Esta tesis se ha enfocado en evaluar el potencial de mejora del control biológico por conservación en huertos frutales y hortícolas en Cataluña, mediante la integración de infraestructuras ecológicas que promuevan y ...
Casasampere Ferrer, Mireia (Data de defensa: 2017-03-24)
Els esfingolípids són lípids complexes derivats de l’esfingosina que a més de servir de base estructural de les membranes cel·lulars, regulen múltiples vies de senyalització, com per exemple l’autofàgia. Entre tots els ...
Cañellas Socias, Adrià (Data de defensa: 2022-07-22)
Colorectal cancer (CRC) kills around 700,000 people worldwide every year. The majority of these deaths are the result of dissemination of the disease to foreign organs. Despite undergoing curative resection of the primary ...
Pertsovskaya, Inna (Data de defensa: 2014-06-25)
Systems Biology opens new frontiers in the studies of complex diseases such as Multiple Sclerosis (MS). The questions that couldn’t be addressed before due to lack of understanding and methodological base, such as the ...
Mazuelas Gallego, Helena (Data de defensa: 2021-01-28)
Neurofibromatosis type 1 (NF1) is a genetic disease caused by inherited mutations in the NF1 gene. NF1 is a cancer predisposition syndrome, and the disease’s hallmark is the appearance of tumors of the peripheral nervous ...
Reginensi Espinoza, Diego (Data de defensa: 2015-05-05)
Las células de la glía envolvente olfatoria surgen hace algunos años como una estrategia prometedora para reparar la médula espinal lesionada. Sin embargo, diversas moléculas inhibitorias están presentes durante largo ...
Paz Domínguez, Joel (Data de defensa: 2021-12-14)
Despite decades of work, the molecular requirements underlying microtubule- organizing center (MTOC) formation at the centrosome remain obscure. Progress is hindered by the complexity of this organelle, which is composed ...
Comas Casellas, Emma (Data de defensa: 2013-03-08)
The main goal of this thesis was to investigate the function of the endogenous CD300f. Initially, CD300f was described as an inhibitory receptor, although some data generated in our lab strongly suggested the possibility ...
Garrido Garcia, Alícia (Data de defensa: 2022-11-10)
[eng] BACKGROUND: High-risk neuroblastoma (NB) represents a heterogeneous group of tumors, whereby patients can display response to treatment and long-term outcome or develop early progressive, chemoresistant disease with ...
Català Moll, Francisco (Data de defensa: 2020-06-08)
Epigenetic factors, such as histone post-translational modifications and DNA methylation, are critical determinants of gene expression, which ultimately defines cell identity and function. Despite intense research in DNA ...
Pijuán Jiménez, Isabel (Data de defensa: 2019-12-02)
During the process of corticogenesis, cortical radial glial cells (RGs) generate sequentially most of the distinct types of neurons and glial cells that will populate the neocortex. The generation of these cells at the ...
Castejón Bueno, Diego (Data de defensa: 2018-05-04)
La presente Tesis Doctoral está centrada en el centollo atlántico (Maja brachydactyla Balss, 1922). Los objetivos incluyen la optimización del cultivo larvario y el estudio ontogénico del sistema digestivo. El cultivo ...
Farré Foix, Marc (Data de defensa: 2016-07-15)
The study of morphology of organisms has become a widely extended scientific discipline since the beginning of the 20th century, when the scientific community began to establish direct relationships between the anatomical ...