Ara mostrant els elements 177-196 de 234

    Patterns of activity in marine planktonic copepods: diel rhythms and driving factors 

    Olivares Requena, Manuel (Data de defensa: 2021-02-19)

    Marine planktonic copepods play a key ecological role in pelagic food webs. The study of their patterns of activity is fundamental in order to better understand the processes involved in the transfer of energy from lower ...

    Patterns of genetic and morphologic diversity in Antarctic sponges = Modelos de diversidad genética y morfológicas en las esponjas antárcticas 

    Carella, Mirco (Data de defensa: 2018-07-13)

    The Antarctic bottoms harbour rich communities of sponges, which play an important role in structuring benthic habitats. Many Antarctic sponge species have been discovered in the past but most of them were poorly described ...

    Pharmaceutical development of nanosystems for the delivery of drugs in epidermis and hair follicles, skin biodistribution studies 

    Pena Rodríguez, Eloy (Data de defensa: 2022-07-18)

    [eng] Different transdermal drug delivery platforms have been developed for epidermal and follicular targeting. Nanoformulations have been developed, optimised and physicochemically characterised with complementary techniques. ...

    PIF3 (phytochrome•interaeting factor 3) and Circadian Clock interaction in the regulation of plant growth 

    Soy Platero, Judit (Data de defensa: 2014-07-17)

    Arabidopsis thaliana seedling growth and development is influenced by both external (such as light and temperature) and internal (like hormones or circadian clock) factors. In short-day (SD) growing conditions, it is known ...

    Plant diversity and vegetation of the Andean Páramo 

    Peyre, Gwendolyn (Data de defensa: 2015-05-12)

    The páramo is a high mountain ecosystem that includes the natural and semi-natural habitats located between the montane treeline and the permanent snowline in the humid Northern Andes. Given its recent origin and continental ...

    Post-transcriptional control of anti-tumor immune responses 

    Fernández Alfara, Marcos (Data de defensa: 2022-04-07)

    Translation of mRNAs into proteins is a highly regulated step of gene expression. In cancer, post-transcriptional and translational control have a critical effect on transformation, controlling proliferation, survival, ...

    Programas de splicing y desarrollo neuronal: función de la quinasa KIS 

    Moreno Aguilera, Marcos (Data de defensa: 2023-09-29)

    [spa] El splicing alternativo es un proceso que además de proporcionar diversidad al transcriptoma y proteoma celular, añade una nueva capa de regulación en la expresión de proteínas y en la función que estas desempeñan. ...

    Protective role of polyethylene glycol 35 against hepatic cold and warm ischemia 

    Silva, Rui Gonçalo Teixeira da (Data de defensa: 2022-09-16)

    Steatotic livers are considerably more prone to IRI, in which turn, it is known to impair mitochondrial function. Our working hypothesis lies on the fact that impaired mitochondrial function and reduced protection against ...

    Proteomic profile in postmortem brain in chronic schizopfrenia 

    Vera Montecinos, América (Data de defensa: 2021-03-23)

    Schizophrenia is a complex psychiatric disorder involving dysregulation of multiple pathways. In the last decades, the cortico-cerebellar-thalamo-cortical circuit has been proposed to play a key role in cognitive impairments ...

    Refining prognosis capacity and implementing priciples of personalized therapies for Neurofibromatosis Type 2 

    Catasús Segura, Núria (Data de defensa: 2022-05-31)

    Neurofibromatosis type 2 (NF2) is an autosomal dominant condition caused by loss of function variants in the NF2 gene. The pathognomonic feature of the disease is the development of bilateral vestibular schwannomas (VS), ...

    Regulation of ribonucleotide reduction in facultative anaerobic pathogens and its influence in bacterial fitness, virulence and biofilm formation 

    Pedraz López, Lucas (Data de defensa: 2020-01-13)

    The perpetuation of life depends on the ability to reproduce. All known forms of life use DNA as genetic information storage. Ribonucleotide reduction is the process by which ribonucleotides (NTPs) are transformed into ...

    Responses to environmental xenobiotics: from endocrine disruption to lipid homeostasis imbalance 

    Dimastrogiovanni, Giorgio (Data de defensa: 2015-09-18)

    Many chemicals are continuously entering into the aquatic environment, as a result of their widespread use, disposal and accidental release. Several of these xenobiotics may disrupt reproductive functions of both vertebrates ...

    Resultados funcionales de la participación de las proteínas insulator en la organización de la cromatina 

    Rodríguez Sánchez, Maria de los Ángeles (Data de defensa: 2019-11-22)

    Las proteínas insulator son componentes esenciales de la organización tridimensional de la cromatina ya que son capaces de establecer interacciones entre regiones distantes de la mediante su capacidad de asociarse a otras ...

    The role of behavioural and feedback mechanisms in mediating herbivory processes in Mediterranean seagrass ecosystems 

    Buñuel Moreno, Xavier (Data de defensa: 2021-07-13)

    The role of consumer-resource relationship is the basis of the structure and functioning of ecological communities. The traditional lens for studying such interactions have tended to omit the importance of the species ...

    Role of Capicua-L in RTK signaling and endocycle regulation 

    Rodríguez Muñoz, Laura (Data de defensa: 2021-05-13)

    The HMG-box protein Capicua (Cic) is a conserved transcriptional repressor with key functions downstream of receptor tyrosine kinase (RTK)-Ras-MAPK signaling pathways. In both Drosophila and mammals, Cic is expressed as ...

    Role of D-fagomine and omega-3 plyunsaturated fatty acids on gut microbia and related metabolic changes in healthy rats and in a model of fat-induced prediabetes 

    Hereu Planellas, Mercè (Data de defensa: 2019-07-19)

    Modern lifestyles in an increasing number of human societies include consuming an excess of saturated fats and refined sugars as well as enjoying microbiologically aseptic environments. Maintaining the appropriate ...

    Role of DPPA3 in hypoxia and tumour dormancy in cancer 

    Cuesta Borràs, Estefania (Data de defensa: 2019-11-28)

    Colorectal cancer (CRC) is a leading cause of death worldwide and tumour recurrence is a frequent complication that arises from minimal residual disease and shows up after a period of clinical dormancy. Slow-cycling cancer ...

    Role of kinase DYRK1A in the neurogenesis of the embryonic telencephalon 

    Trujillano Fernández, Alejandro (Data de defensa: 2024-02-08)

    [eng] DYRK1A is a kinase that is expressed in virtually all tissues and cell types and is implicated in human diseases. Several studies indicate that DYRK1A is a dose-dependent gene with a prevalent function in brain ...

    Role of MAF in bone metastasis 

    Bellmunt i Tarragó, Anna (Data de defensa: 2017-12-15)

    The identification of genes that mediate metastasis is pivotal to better understand the mechanism, to develop novel drugs and to stratify patients with highest risk and consecutively administrate them preventive treatments. ...

    Role of Mfn2 in Macrophage Inflammatory Responses 

    Tur Torres, Juan (Data de defensa: 2017-03-22)

    Mitochondria are well known for their role as bioenergetic and biosynthetic organelles. Recently, they also have emerged as one of the main regulators of innate immune responses, mostly for its ability to modulate several ...