Universitat de Barcelona
Now showing items 120-139 of 229
The major landmark in modern genomic and biological research has been the first survey of the entire human genome. On June 2000 the staging of Bill Clinton along with Craig Venter and Francis Collins extolled how genome ...
Proteins play a crucial role in virtually every biological process taking place within our cells. Most of the times, proteins do not participate in these processes alone but forming complexes of two or more proteins. ...
Proteins are large macromolecules constituted by amino acids that are responsible for most of the biological processes within a cell. Proteins showing high complementary affinity may bind forming protein-protein complexes. ...
Recent policies on the ban of fishing discards and the closure of open-air landfills are expected to reduce amount of predictable anthropogenic food subsidies (PAFS) for seabirds. To forecast the ecological consequences ...
Extensive farmland ecosystems are widespread and biodiversity-rich, yet they face important human pressures since the beginning of agriculture intensification, which is leading them into a severe biodiversity crisis. As a ...
[eng] In recent years, the genetics field has placed a significant emphasis on identifying and characterizing genetic factors contributing to complex diseases, alongside environmental factors. Genome-wide association ...
[eng] Malignant peripheral nerve sheath tumors (MPNSTs) are rare soft-tissues sarcomas of the peripheral nervous system (PNS) with poor prognosis and lack of therapeutic options. Complete resection with wide margins of the ...
[eng] The most severe form of malaria, caused by Plasmodium falciparum parasites, still kills over half a million people every year, most of them children under the age of five. Despite huge research efforts, reduction in ...
Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiac disease and a frequent cause of heart failure and sudden cardiac death. HCM is a highly complex condition defined by clinical and genetic heterogeneity. ...
Parkinson’s disease (PD) is an incurable, chronically progressive disorder of old age leading to premature invalidity and death. Clinically, PD is characterized by classical motor syndrome linked to a progressive loss of ...
Genetically tractable models such as Drosophila melanogaster may help to identify new approaches to halt malignant growth. During my doctoral thesis, I performed a screen to find mitochondrial genes required for the growth ...
During recent years, jellyfish blooms have become in a passionate issue among marine scientists with a series of studies and reviews. The main concern about this blooms are related with ecosystem and socio-economic impacts ...
[eng] Linker histones are essential proteins involved in higher-order chromatin structures and architectural functions. However, their roles extend beyond structure, encompassing various chromatin metabolic processes such ...
Intrinsically disordered (ID) proteins or regions are protein sequences that lack stable secondary and tertiary structures. ID proteins are particularly prone to undergo liquid- liquid phase separation (LLPS). The structures ...
IPSC are potent tools in the creation of disease models for both basic studies on the disease and testing of potential therapeutical drugs. In this context, it has been developed the derivation of iPSC from patient fibroblasts ...
Iberian Pinus uncinata tree-growth variability and its responses to climate are analyzed by means of dendrochonological methods from an individual- to a population-level scale across its distribution area in the Iberian ...
La patologia associada a l’hemostàsia primària ha estat clàssicament relacionada amb diàtesi hemorràgica (malaltia de von Willebrand, Síndrome de Bernard- Soulier, malaltia de Glanzmann, trombopènia, etc) on s’ha valorat ...
The symbiotic lifestyle represents a fundamental contribution to the diversity of marine ecosystems. Sponges are ideal models to study symbiotic relationships from evolutionary and ecological points of view since they are ...
La Esclerosis Múltiple (EM) afecta preferentemente a la conectividad cerebral lesionando los axones de forma irreversible, siendo esta lesión la principal causa de la discapacidad permanente de los pacientes. El daño axonal ...
La presente tesis doctoral se ha centrado en investigar los procesos de desregulación en la metilación del DNA y de microRNAs en dos tipos celulares implicados en la patogenia de la artritis reumatoide, cuya función se ...
