Mostrando ítems 46-65 de 85
Bednarczuk, Lukasz (Fecha de defensa: 2017-01-11)
In this work, the effect of CO2 on the hydrogen production under substoichiometric ethanol steam reforming (ESR) conditions over nickel based catalysts was studied. A special emphasis was focused on the application of ...
Tolrà Rovira, Roser (Fecha de defensa: 2017-07-21)
L'objectiu principal d'aquesta Tesi doctoral ha estat l’obtenció d’una via alternativa a les existents per a l'obtenció d'un intermedi clau, 1, en la síntesi d'un fàrmac anticoagulant. La nova via havia de ser novedosa i ...
Segovia Laserna, Rosario (Fecha de defensa: 2022-03-08)
After decades of exorbitant antibiotic misuse and overuse in human medicine, agriculture and livestock industry, multidrug resistant bacteria (MDR) have become a major medical concern. In this regard, the design of new, ...
Gandioso Ubieto, Albert (Fecha de defensa: 2018-11-12)
In the present Thesis, it has been carried out the development of new chemical tools for the diagnosis and treatment of cancer through the use of light as an external factor. On the one hand, light can be used to control, ...
Brun Cubero, Omar (Fecha de defensa: 2016-07-27)
An alternative allowing diene-derivatised polyamides to be used in Diels-Alder conjugation reactions has been explored and developed. In this methodology, conjugation takes place between a fully protected, resin-linked ...
Arbesú Andrés, Miguel (Fecha de defensa: 2018-03-02)
c-Src is a central player in several cellular signaling pathways. It controls impor- tant cellular processes like cellular proliferation, survival or motility. Therefore, a number of tumoral diseases have been related to ...
San Juan Ocete, Alexis (Fecha de defensa: 2018-07-13)
Estudios previos de nuestro grupo de investigación describieron moléculas orgánicas heterocíclicas, aparentemente de capas cerradas que presentan carácter birradical triplete asequible térmicamente. La formación de esta ...
Vázquez Bigas, Guillem (Fecha de defensa: 2019-03-22)
Alzheimer’s disease (AD), for which no cure is known yet, is currently the most prevalent cause of dementia for the elderly population. The aberrant aggregation of β-amyloid peptide (Aβ) is believed to trigger the events ...
Arribas Crovara, Maria Fernanda (Fecha de defensa: 2022-11-11)
[spa] En el primer bloque de la tesis describimos nuestra aproximación a la síntesis total de la Palmerolida D, un compuesto de gran interés, tanto por sus propiedades antitumorales como por la diversidad de reacciones ...
Carneros García, Héctor (Fecha de defensa: 2018-06-29)
El desarrollo de métodos para la creación de nuevos enlaces carbono-carbono de forma sostenible y selectiva es clave en la química orgánica actual. En las últimas décadas, ha aumentado de gran manera el interés en llevar ...
Arlegui Chamizo, Aitor (Fecha de defensa: 2019-12-16)
La quiralidad es una propiedad fundamental de la naturaleza. La vida en la Tierra se basa en la quiralidad. Casi todos los compuestos quirales presentes en los organismos vivos se encuentran solo en una de sus formas ...
Salomó i Prat, Ernest (Fecha de defensa: 2018-10-19)
Asymmetric hydrogenation of double bonds by means of organometallic catalysis is a powerful tool for organic synthesis; it is an efficient and simple method to produce valued chiral compounds. Among the many different ...
Gallen Ortiz, Albert (Fecha de defensa: 2019-02-01)
The Thesis deals with the preparation, coordination chemistry and use in asymmetric homogeneous catalysis of several optically pure P-stereogenic ligands containing a tert-butylmethylphosphino fragment. In the first part ...
Rojo Solé, Josep Maria (Fecha de defensa: 2022-11-02)
[eng] P-Stereogenic ligands have demonstrated to be highly efficient for asymmetric catalysis, especially in metal-catalyzed asymmetric hydrogenation reactions. Among them, those bearing bulky substituents at phosphorus ...
Mancinelli, Andrea (Fecha de defensa: 2017-04-21)
The development of selective methods for the direct conversion of carbon−hydrogen bonds into carbon-heteroatom and carbon−carbon bonds remains a critical challenge in organic chemistry. An interesting approach to address ...
Escriche Tur, Luis (Fecha de defensa: 2016-11-21)
The main objective of this work is the synthesis of manganese compounds and hybrid materials that may be relevant from a bioinorganic and magnetic point of view. The developed strategy comprises three main steps that form ...
Llorens Palomo, Lluís (Fecha de defensa: 2019-10-28)
Cucurbiturils are known to present potential applications in molecular recognition, self- assembly, and nanotechnology. The discovery of ultra-high affinity CB–guest complexes with binding constant values similar than those ...
Lobo Ruiz, Ariadna (Fecha de defensa: 2019-05-10)
Peptides and proteins are essential substances for living organisms, as they can be found in every cell and tissue and are involved in many biological and physiological processes. Given their intrinsic properties and their ...
Flores Teloxa, Saúl (Fecha de defensa: 2020-12-01)
En esta Tesis Doctoral se han explorado y optimizado nuevas metodologías enantioselectivas y directas de formación de enlaces carbono-carbono catalizadas por complejos quirales de níquel(ll). Esencialmente, se han estudiado ...
Fernández-Valparís Morán, Javier (Fecha de defensa: 2019-07-15)
En la presente tesis doctoral se ha desarrollado y expandido la metodología estereoselectiva, catalítica y de tipo directa en la cual enolatos de níquel(II) de N-acil tiazolidintionas quirales reaccionan con un amplio grupo ...