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Showing 10 out of a total of 22 results for collection: Departament de Farmacologia, Toxicologia i Química Terapèutica. (0.057 seconds)
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(Date of defense: 28-09-2017)Chiral amino alcohol derived lactams are a valuable scaffold for the enantioselective synthesis of alkaloids. In the present thesis the potential of this methodology was expanded and to demonstrate the synthetic utility ...
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(Date of defense: 26-09-2017)1. It was observed that the interaction of imines and isocyanides in the presence of a Lewis acid can lead to a variety of scaffolds including α-aminoamides, α-aminoamidines, indoles and diiminoazetidines. The reaction ...
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(Date of defense: 21-10-2016)This doctoral thesis consists in two main parts. The first part focus in the study of methodology development in order to bring modularity and diversification to compounds studied within the research group. It consists ...
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(Date of defense: 02-11-2016)Sphingolipids (SLs) are essential structural and signaling molecules of eukaryotic cells. An important group of SLs metabolites are those showing a phosphate group at the C1‒ OH. Among them, sphingosine‒1‒phosphate (S1P) ...
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(Date of defense: 17-07-2017)The present thesis is included in the area of Nanomedicine and supramolecular chemistry, focused on the design and preparation of different nano and microtools for delivery, therapy and sensing. Initially, the synthesis ...
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(Date of defense: 20-12-2016)Durante este trabajo de tesis doctoral se ha demostrado que las cloroacetamidas son intermedios de gran utilidad para la síntesis de heterociclos nitrogenados a través de procesos radicalarios o no radicalarios. En este ...
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(Date of defense: 28-07-2016)The first objective of this Thesis was the study of the preparation of octhydro-1H-cyclopenta[b]pyridines and octahydro-1H-indoles, through the synthesis of (R)-phenylglycinol derived tricyclic lactams. Following the ...
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(Date of defense: 19-07-2016)En la present tesi doctoral s’ha desenvolupat una estratègia per obtenir els esquelets dels quatre alcaloides licopodi representatius a partir d’un mateix intermedi sintètic comú 1, de manera semblant al procés que té lloc ...
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(Date of defense: 05-07-2016)Although sygma-aryl and sygma-vinylpalladium(II) complexes are commonly used as electrophiles in C—C bond forming reactions, recent research has demonstrated that the same palladium intermediates can also react with ...
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(Date of defense: 13-01-2017)L’objectiu de la present tesi doctoral consisteix en desenvolupar molècules policícliques de baix pes molecular que tinguin com a diana tres canals iònics específics: la viroporina A/M2 del virus de la grip, el receptor ...
