Browsing Departament de Bioquímica i Biomedicina Molecular by Title

Now showing items 58-66 of 66

Regulació del transportador de nucleòsids d'alta afinitat hCNT3 per proteïnes d'interacció

Casulleras Gras, Olga (Date of defense: 2018-12-14)

Els transportadors de nucleòsids pertanyen a les famílies gèniques SLC28 i SLC29 que codifiquen pels transportadors de nucleòsids concentratius (hCNTs) i transportadors de nucleòsids equilibratius (hENTs), respectivament. ...

Regulation of brown adipose tissue metabolism by TP53INP2 = Regulació del metabolisme del teixit adipós marró per mitja de TP53INP2

Sabaté Pérez, Alba (Date of defense: 2019-10-21)

Overweight and obesity have increased dramatically during recent decades becoming a major health problem for which therapeutic options are limited. Thus, there is an urgent need to develop new safe pharmacological therapies. ...

Regulation of hepatic metabolism by the autophagic protein TP53INP2

Frager, Petra (Date of defense: 2022-10-28)

[eng] Decreased physical activity and increased consumption of energy-rich food are hallmark lifestyle modifications that developed and amplified over the course of only a few decades. These changes in our daily behavior ...

Regulatory subunits controlling the Kv1.3 channelosome

Cassinelli, Silvia (Date of defense: 2023-12-15)

[eng] The Kv1.3 voltage-dependent potassium channel plays a crucial role in the immune response participating in various cellular functions like proliferation, activation, and apoptosis. The aberrant expression of this ...

Relevant Molecular and Functional G.Protein Coupled Receptor Interactions in Neuroinflammation and Addiction = Interaccions moleculars i funcionals de receptors acoblats a proteïna G rellevants en neuroinflamació i addició

Angelats Canals, Edgar (Date of defense: 2018-09-14)

G-protein coupled receptors (GPCR) constitute a complex and versatile superfamily of membrane receptors with relevance in maintaining homeostasis. The thesis project has focused in members of this superfamily: the CB1 and ...

The role of the G-protein coupled receptor 120 (GPR120) on the FGF21 system in white and brown adipose tissues

Quesada López, Tania Paloma (Date of defense: 2018-07-09)

Obesity prevalence has tripled in the last fifty years. For this reason, it is considered the pandemic of the century. It is characterized by the accumulation of metabolic abnormalities triggered by an increase in the size ...

Study of the metabolic reprogramming associated to metastasis in colon cancer

Tarragó Celada, Josep (Date of defense: 2020-09-16)

Metastasis is the main cause of cancer-related deaths and it is of great biomedical importance to develop new therapeutic strategies that specifically target metastatic cells. Therefore, a better comprehension of the process ...

Turnover of voltage-gated potassium channel Kv 1.3

Styrczewska, Katarzyna (Date of defense: 2017-09-22)

Voltage-gated K channels (Kv) is large family of channels that are expressed in both excitable and non-excitable cells. In excitable cells they contribute to the control of resting membrane potential and action potentials ...

Using pacient-specific IPSC derived dopaminergic to investigate Parkinson's disease: a new prospective in stem cell research and application = Utilització de neurones dopaminèrgiques específiques de pacients derivades de cèl·lules pluripotents induïdes (IPSC) en la investigació de la malaltia de Parkinson: una nova perspectiva en la investigació amb cèl·lules mare i les seves aplicacions

Torrent Juan, Roger (Date of defense: 2016-06-02)

Parkinson’s disease (PD) is an incurable neurodegenerative disorder, mainly characterized by a progressive loss of midbrain dopaminergic (DA) neurons, located in the substantia nigra pars compacta (SNpc), and frequently ...