Ara mostrant els elements 27-34 de 34

    Regulació i funció en resposta a diferents tipus d’estrès de la CaMKK Ckk2 

    Martin Ramos, Edgar (Data de defensa: 2021-04-26)

    Les proteïnes de la família de les CaM quinases (CAMK en anglès), l’activitat de les quals és dependent del complex calci-calmodulina, estan implicada en funcions cel·lulars com la regulació de l’expressió gènica, la ...

    Regulación de la separasa mediada por el nuevo papel de Sak1 en mitosis 

    Vaquero Pelaz, David (Data de defensa: 2024-02-02)

    [spa] El ciclo celular es un conjunto ordenado de sucesos que tienen como fin el crecimiento de una célula y su división en dos células hijas. Uno de los sucesos más relevantes en el ciclo celular es la correcta segregación ...

    Regulation of synthesis, transport and accumulation of lipids in Lipid droplets by Acetyl-CoA carboxylase and Caveolins. How cells accumulate lipids but reduce lipotoxicity 

    Morales Paytuví, Frederic (Data de defensa: 2022-02-04)

    The following sections of the thesis are divided in two parts corresponding with the two projects conducted, whose objectives are stated below. 1. Caveolin in the endoplasmic reticulum During the last years, the ...

    Replication stress: mechanisms and molecules involved in DNA replication progression and reinitiation 

    Feu i Coll, Sònia (Data de defensa: 2019-03-28)

    This thesis investigates the mechanisms that are activated in response to replication stress induced with hydroxyurea, an agent that causes deoxyribonucleotides depletion and arrest cells in S phase, in the non-transformed ...

    Role of polyreactive autoantibodies in the physiopathology of Sjögren’s Syndrome 

    Gutiérrez Cózar, Rebeca (Data de defensa: 2024-01-22)

    [eng] Sjögren's syndrome (SjS) is a chronic autoimmune disease that mainly affects the exocrine glands and is characterized by the presence of antinuclear antibodies such as anti-Ro52 and anti-dsDNA. Our previous analysis ...

    Study of pro-apoptotic protein RTP801 homeostasis and its regulation by NEDD4 in Parkinson's disease 

    Canal de la Iglesia, Mercè (Data de defensa: 2016-06-01)

    Parkinson’s disease (PD) is characterized by the loss of dopaminergic neurons of the Substantia Nigra pars compacta (SNpc) and the presence of cytoplasmic protein inclusions named Lewy Bodies. Current treatments are directed ...

    Study of the mTOR pathway in neurodegenerative diseases: from synapses to genes 

    Martín Flores, Núria (Data de defensa: 2018-12-14)

    Huntington's disease (HD) and Parkinson's disease (PD) are devastating neurodegenerative diseases that progress with the death of selective neuronal subpopulations. Neuronal dysfunction and death are consequence of multiple ...

    Technological insights into a histopathological and protein composition analysis of aortic aneurysms in Marfan syndrome 

    López Guimet, Júlia (Data de defensa: 2018-04-25)

    The aorta is the main artery of the body, whose function is to collect the blood ejected by the heart and distribute it to all tissues. The elastic degree of the aortic wall necessary to withstand blood pressure is mainly ...