Morales Paytuví, Frederic (Date of defense: 2022-02-04)
The following sections of the thesis are divided in two parts corresponding with the two projects conducted, whose objectives are stated below. 1. Caveolin in the endoplasmic reticulum During ...
Feu i Coll, Sònia (Date of defense: 2019-03-28)
This thesis investigates the mechanisms that are activated in response to replication stress induced with hydroxyurea, an agent that causes deoxyribonucleotides depletion and arrest cells in S phase, ...
Martin Ramos, Edgar (Date of defense: 2021-04-26)
Les proteïnes de la família de les CaM quinases (CAMK en anglès), l’activitat de les quals és dependent del complex calci-calmodulina, estan implicada en funcions cel·lulars com la regulació de l’expressió ...
Suelves Caballol, Núria (Date of defense: 2018-07-23)
Huntington’s disease (HD) is a rare genetic disorder caused by an aberrant expansion of a CAG trinucleotide in the huntingtin gene (Htt). The neuropathology of the disease is characterized by progressive ...
López Guimet, Júlia (Date of defense: 2018-04-25)
The aorta is the main artery of the body, whose function is to collect the blood ejected by the heart and distribute it to all tissues. The elastic degree of the aortic wall necessary to withstand blood ...
Durán Rodríguez, Rodrigo (Date of defense: 2022-01-28)
Partint dels resultats previs obtinguts per aquest grup d’investigació, es planteja la següent hipòtesi de treball: “La proteïna p27 és un regulador de la via de Notch. Aquesta regulació es realitzaria, ...
Romero Moya, Damià (Date of defense: 2017-01-16)
Homeostasis of the hematopoietic stem/progenitor cell pool relies on a finely tuned balance between self-renewal, differentiation and proliferation. Recent work has revealed the importance of mitochondria ...
Duch Gili, Paula (Date of defense: 2022-03-14)
Increased expression of TIMP-1 is associated with poor prognosis in virtually all cancer types, including lung cancer. However, how TIMP-1 is regulated in lung cancer and how it drives tumor progression ...
Unzueta Payeras, Fernando (Date of defense: 2023-07-28)
[cat] El nostre laboratori està centrat en l’estudi de la resposta a l’estrès replicatiu, ja que aquest estrès està relacionat amb la tumorigènesi i la seva resposta és un mecanisme fonamental per ...
García Díaz, Roberto (Date of defense: 2023-05-26)
[spa] Debido a la importancia de la modulación del NMDAR, en el grupo de investigación de proteínas (GRIP) se han diseñado una serie de péptidos derivados de la Conantokina-G (Con-G), un péptido ...