Ara mostrant els elements 258-277 de 315
Figueiredo Escribá, Carlos de (Data de defensa: 2019-05-28)
Desde los años 90 numerosos han sido las contribuciones de la comunidad científica en aras a minimizar el impacto de los EM en la salud pública presentándose múltiples propuestas desde otras tantas perspectivas para que ...
Zinna, Valentina Maria (Data de defensa: 2021-07-09)
Circadian rhythms regulate tissue physiology throughout the day in response to environmental cues. The primary entraining cue for the mammalian circadian clock is light, which is perceived by the retina and transmitted to ...
Toribio Isaías, Luis Daniel (Data de defensa: 2019-12-18)
The aim of this project is to structurally characterize proteins involved in bacterial signal transduction systems by applying X-ray crystallography. Bacteria use signal transduction systems to react in response to any ...
López Ortiz, Manuel (Data de defensa: 2023-05-24)
[eng] In this thesis manuscript entitled “Single molecule electrochemical studies of photosynthetic complexes” I study the Photosystem I (PSI) protein complex to characterize fundamental processes of the PSI function. PSI ...
Moner del Moral, Verónica (Data de defensa: 2018-12-12)
El estrato córneo (SC) es la capa más superficial de la epidermis. Su función es actuar como barrera, evitando la pérdida de agua y la entrada de microorganismos. El SC está formado por corneocitos rodeados por lípidos que ...
Lozano Mena, David (Data de defensa: 2017-07-10)
En la present Tesi Doctoral s’ha desenvolupat una metodologia sintètica per accedir a compostos policíclics complexos funcionalitzats de manera senzilla i eficaç, amb l’objectiu de poder generar a partir d’aquests un alquè ...
Moreno Fontalba, Carlos José (Data de defensa: 2023-07-21)
[eng] Concurrent or consecutive enzymatic cascade reactions have received special attention in the development of synthetic strategies for complex molecules. The advantage of these strategies is that they eliminate the ...
Navarro Rivera, Lorena (Data de defensa: 2018-10-16)
Esta tesis doctoral está enfocada a la investigación de nuevos agentes con potencial actividad antiinflamatoria y antitumoral mediante la inhibición de enzimas básicas para la progresión de la inflamación como la ciclooxigenasa ...
Khorsandi, Danial (Data de defensa: 2021-11-19)
Dermatitis is a chronic inflammatory skin disease, described by intensive pruritus and eczematous lesions of skin. In most of the patients with Dermatitis, a long-lasting cycle of itch-scratch roots produces substantial ...
López Cerro, Maria Teresa (Data de defensa: 2018-06-29)
Chlamydomonas reinhardtii has emerged as a promising alternative host for recombinant protein expression. Despite its advantageous characteristics and low-cost production, its use is hampered by low expression levels of ...
Medina Bernal, Ana del Rocío (Data de defensa: 2021-11-19)
Determining and understanding protein structure in atomic detail is a fundamental process to the advancement of biotechnology and biomedicine, shedding light the role of macromolecules and their complexes, their biological ...
Jiménez Panizo, Alba (Data de defensa: 2021-12-14)
El receptor de glucocorticoides (GR) es un factor de transcripción que se expresa de forma ubicua y controla procesos esenciales para la vida como el metabolismo, la inflamación y la homeostasis. Aunque se han publicado ...
Ruiz Arroyo, Víctor Manuel (Data de defensa: 2020-10-23)
Zika virus (ZIKV) belongs to the Flaviviridae family and constitute an important public health concern since ZIKV infection produced devastating effects in new born infants. Flaviviruses present a positive sense single ...
Alcaide i Jiménez, Adrià (Data de defensa: 2023-12-01)
[eng] Cholera is an acute life-threatening infection caused by the bacterium Vibrio cholerae, a devastating pathogen in least developed countries, which caused six world pandemics, apart from the ongoing one. Despite current ...
Szulc, Elizbieta Maria (Data de defensa: 2020-01-09)
Androgen receptor is a transcription factor that plays a key role in prostate cancer development and progression. Its N-terminal intrinsically disordered activation domain is an example of ill- structured negatively charged ...
Suñol Moreno, David (Data de defensa: 2016-12-19)
The present thesis is divided in three different but related projects. In the first project, the interaction between TGIF1 and SMAD proteins is investigated. TGIF1 is a transcriptional suppressor that prevents the gene ...
García Lema, Jorge (Data de defensa: 2020-10-08)
Adenosine deaminase acting on tRNAs (ADAT) is a eukaryotic heterodimer, composed by ADAT2 and ADAT3, that catalyses the deamination of adenosine-to-inosine in the anticodon loop of tRNAs. ADAT proteins are essential for ...
Schmitz, Claus-A. (Data de defensa: 2023-04-26)
[eng] We investigated the structure function relationship of PorX by combined biophysical experiments and enzymatic assays. As a regulator of the type 9 secretion system (T9SS) of the human pathogen Porphyromonas gingivalis ...
Cuppari, Anna (Data de defensa: 2016-12-21)
The mitochondrial transcription factor A, TFAM, has a dual function in the organelle: it activates mitochondrial DNA transcription by binding to the HSP and LSP promoters, while in higher concentrations compacts the mtDNA. ...
Szura, Arkadiusz Damian (Data de defensa: 2023-03-17)
[eng] The emergence and spread of antibiotic resistance among bacteria has become an undisputed global problem and one of the greatest threats to public health in the 21st century. The widespread, excessive and uncontrolled ...