Facultat de Farmàcia i Ciències de l'Alimentació

Recent Submissions

Investigating abdominal aortic aneurysm mechanisms: searching for new therapeutic targets to restrain inflammation and vascular remodelling 

Puertas Umbert, Lídia (Date of defense: 2024-06-21)

[eng] Abdominal aortic aneurysm (AAA) is a prevalent vascular degenerative disease defined as a focal and permanent dilation of the aorta at the abdominal level. The progressive weakening of the aortic wall can ultimately ...

Effect of different types of Mediterranean diet, types and quality of breakfasts, and sourdough bread on cardiometabolic risk in a population with high cardiovascular risk 

Pérez Vega, Karla Alejandra (Date of defense: 2024-12-03)

[eng] Cardiovascular diseases are a major public health concern in Spain, where they are the leading cause of death. Lifestyle interventions, and diet in particular, are useful strategies to prevent cardiovascular disease ...

Pegilación y liofilización de nanopartículas sólidas lipídicas con colesteril oleato como vectores de ácidos nucleicos 

Narváez Narváez, David Andrés (Date of defense: 2024-05-29)

[spa] Las nanopartículas catiónicas sólidas lipídicas (cSLN) han surgido como una herramienta prometedora en terapias genéticas y de ARN. Esta investigación se enfocó en mejorar la formulación existente de SLNs con colesteril ...

Role of HIVEP2 in drug-tolerant persister cancer cells and tumor recurrence 

Mur Espinosa, Alex (Date of defense: 2024-12-17)

[eng] Colorectal cancer (CRC) is a leading cause of death worldwide and tumor recurrence is a frequent complication that arises from minimal residual disease (MRD). Patients can relapse months or even years after an apparent ...

Mecanismos de señalización en el trasplante hepático de donantes con criterio extendido 

Micó Carnero, Marc (Date of defense: 2024-11-22)

[spa] En la práctica clínica, el trasplante de hígado supone una de las pocas soluciones a enfermedades hepáticas en estado terminal. Multitud de personas fallecen esperando un injerto hepático debido a la escasez de ...

Role of conjugated sterols homeostasis in plant development and stress response 

Lopez Tubau, Joan Manel (Date of defense: 2024-12-19)

[eng] Phytosterols are a family of triterpenoid compounds that occur in free form (FS) or conjugated as steryl esters (SE), steryl glycosides (SG) and acylated steryl glycosides (ASG). Free sterols and their glycosylated ...

CPEB4 regulation of vasculogenic mimicry in liver cancer: mechanisms and therapeutic implications 

Iralde Cárdenas, Beatriz (Date of defense: 2024-12-12)

[eng] BACKGROUND: Hepatocellular carcinoma (HCC) poses a significant clinical challenge due to its complex vascular abnormalities and the regulatory mechanisms underlying tumor progression. Vasculogenic mimicry (VM), a ...

Effects of Mediterranean Diet on Cardiometabolic Biomarkers in Randomized Clinical Trials: Molecular Mechanisms 

Hernando Redondo, Javier (Date of defense: 2024-12-13)

[eng] Cardiovascular diseases (CVDs) remain the leading cause of death worldwide. This global burden continues to rise due to aging populations, unhealthy diets, sedentary lifestyles, and increasing rates of obesity and ...

Explorant tres segles de col·leccions de l’Institut Botànic de Barcelona: fonts de coneixement per a diversos aspectes de la botànica i de la història de la ciència 

Gavioli Forni, Laura (Date of defense: 2024-11-29)

[cat] En aquesta tesi doctoral, mitjançant l’estudi dels herbaris històrics i dels materials d’arxiu de l’Institut Botànic de Barcelona (IBB), s’amplia el coneixement sobre alguns botànics vinculats a aquestes colꞏleccions ...

Nanopartículas lipídicas de Apigenina y Melatonina en farmacoterapia oncológica y ocular 

Bonilla Vidal, Lorena (Date of defense: 2024-11-22)

[spa] Los sistemas nanoestructurados lipídicos (NLC) han surgido como una herramienta prometedora en la nanomedicina, ofreciendo una gran versatilidad para la administración dirigida de fármacos. Su biocompatibilidad, ...

The impact of soluble epoxide hydrolase inhibition and epoxyeicosatrienoic acids on early-life microglia activation and neuroinflammatory responses in the brain 

Bartra i Cabré, Clara (Date of defense: 2024-09-26)

[eng] Alzheimer's disease (AD) is a neurodegenerative disorder characterized by a progressive cognitive decline and is the most common cause of dementia worldwide. AD has a complex multifactorial aetiology influenced by ...

BODIPY-functionalized nanostructured materials for intracellular glutathione sensing and mitochondria bioimaging 

Bagherpour, Saman (Date of defense: 2025-11-15)

[eng] In the present thesis, molecular probes and functionalized nanostructured materials were prepared for the detection and quantification of intracellular glutathione (GSH), as well as mitochondria bioimaging. For this ...

Impact of dietary inflammatory potential and (poly)phenols on cardiometabolic health 

Arancibia Riveros, Camila (Date of defense: 2024-12-05)

[eng] Obesity and cardiometabolic diseases (CMD) represent a growing health problem worldwide. The prevalence of CMD and metabolic syndrome (MetS) is increasing in adults and children. The early development of these ...

Innovación en la detección de Legionella y en el cultivo de bacterias exigentes 

Casino Alcalde, Pablo (Date of defense: 2024-01-19)

[spa] La legionelosis o enfermedad del legionario es una enfermedad infecciosa provocada por Legionella, una bacteria gramnegativa aeróbica estricta y un patógeno intracelular facultativo. Se transmite en humanos principalmente ...

Optimización del diagnóstico parasitológico de la leishmaniosis tegumentaria y caracterización de especie/s de Leishmania causantes del cuadro clínico en Cochabamba (Bolivia) 

Torrico de Solano, Mary Cruz (Date of defense: 2024-02-01)

[spa] En Bolivia, la leishmaniosis tegumentaria (LT) abarca siete de los nueve departamentos, siendo uno de los países que presenta un mayor número de casos de leishmaniosis mucosa (LM) o leishmaniosis mucocutánea (LMC). ...

Study on Effects of Metformin and Transplantation of NPCs Separately and in Combination on Restores Cognitive Dysfunction and Histopathological Deficits in Mouse Model of Sporadic Alzheimer’s Disease 

Rabieipoor, Saghar (Date of defense: 2024-01-23)

[eng] LOAD is a type of metabolic disorder known as type 3 diabetes. Metformin, a well-known anti-diabetic medication, has been introduced as a neuroprotective agent in recent years. On the hand, identifying the factors ...

Phenolic compounds and other constituents of extra virgin olive oil: Exploring the impact of cultivar, ripeness, malaxation, and high hydrostatic pressure 

Olmo Cunillera, Alexandra (Date of defense: 2024-02-09)

[eng] Olive oil represents a very important part of the economy of Spain and Catalonia. The value of this product, specifically extra virgin olive oil (EVOO), lies in its quality, both in terms of organoleptic and nutritional ...

The Contribution of the Polyamine Spermine to Plant Defense 

Zhang, Chi (Date of defense: 2024-07-11)

[eng] Polyamines are essential in plant defense, with putrescine (Put), spermidine (Spd), and spermine (Spm) being the most abundant types. In response to various pathogens, including Pseudomonas syringae pv. tomato DC3000 ...

Prior knowledge and verification in macromolecular crystallography 

Jiménez Mellado, Elisabet (Date of defense: 2024-07-25)

[eng] Structural biology is essential for understanding the structure and dynamics of biological macromolecules, proteins, nucleic acids and their complexes, and to derive how the alterations produced in their structure ...

Characterization and prospective applications of melanin from black fungi in environmental biotechnology 

Medina-Armijo, Cristy Alejandra (Date of defense: 2024-07-05)

[eng] Black fungi comprise a diverse group of ascomycetes characterized by their dark pigmentation due to the presence of melanin within their cells. This melanization process confers black fungi with a remarkable adaptability ...