Mostrando ítems 170-189 de 315
Hernández Madrigal, Miguel (Fecha de defensa: 2022-06-17)
Tumours grow in a self-imposed hypoglycaemic microenvironment due to their exacerbated metabolic needs. To thrive in these harsh conditions, malignant cells must adapt their own metabolic routes and hijack the host nutrient ...
Ruiz-Loscertales, H. (Héctor) (Fecha de defensa: 2017-07-17)
Los Sistemas Personalizados de Dosificación (SPD) son un sistema de reacondicionado donde el farmacéutico organiza los medicamentos de forma farmacéutica sólida que toma un determinado paciente durante una semana, siguiendo ...
Seuma Areñas, Mireia (Fecha de defensa: 2023-01-18)
[eng] Proteins can adopt multiple conformations and material states, from soluble states to self- assemblies, such as liquid condensates or amyloids. Protein aggregation has been associated with many human diseases but how ...
Riera Armengol, Pau (Fecha de defensa: 2020-09-23)
El càncer colorectal (CCR) és una neoplàsia molt freqüent que causa una elevada mortalitat arreu del món. Els fàrmacs més utilitzats en el seu maneig són quimioteràpics (fluoropirimidines, oxaliplatí i irinotecan), agents ...
Corpas Expósito, Rubén (Fecha de defensa: 2016-12-22)
El aumento de la esperanza de vida poblacional que ha tenido lugar en las últimas décadas, previsiblemente conducirá a un incremento de la incidencia de enfermedades asociadas con la edad, incluyendo la demencia. La principal ...
Ballester Servera, Carme (Fecha de defensa: 2023-10-16)
[spa] La calcificación cardiovascular (CCV) afecta a arterias y válvulas comprometiendo su normal funcionamiento y aumentando el riesgo de sufrir accidentes cardiovasculares y de desarrollar hipertrofia cardíaca e insuficiencia ...
Ramírez Corpas, Lorena (Fecha de defensa: 2023-01-20)
[spa] Alrededor del 10% de los pacientes con cáncer colorrectal metastático (mCRC) presentan la mutación BRAF(V600E), mutación que está asociada a una peor respuesta al tratamiento estándar con agentes quimioterapéuticos ...
Avalos de León, Cindy Guadalupe (Fecha de defensa: 2020-07-21)
Cada año, miles de personas fallecen a causa de enfermedades hepáticas en estado terminal, siendo la falta de injertos hepáticos un problema sin resolver en la práctica clínica. Para tratar de resolver esta grave situación ...
Bernat Peguera, Adrià (Fecha de defensa: 2019-09-20)
La mayoría de los carcinomas escamosos de piel (cSCCs) se tratan con éxito mediante escisión quirúrgica. Sin embargo, el 5-8% de los casos desarrollan recurrencias, las cuales están asociadas a un crecimiento agresivo, ...
Rinaldi de Alvarenga, José Fernando (Fecha de defensa: 2019-07-18)
Cooking made humans evolve. Cooking modified our gastrointestinal system, reducing the gut size and energy expenditure for digestion, which enabled the appearance of a more energy-dependent brain. Cooking process have ...
Monaco, Paola (Fecha de defensa: 2022-09-23)
[eng] Rhabdomyosarcoma (RMS) is the most prevalent soft tissue sarcoma (STS) in children and adolescents. The Alveolar subtype (ARMS) is driven by PAX3-FOXO1, a fusion protein originated from a chromosomal translocation. ...
Burciaga Monge, Alma Delia (Fecha de defensa: 2020-01-31)
Los esteroles son una familia de compuestos triterpénicos que se presentan en forma libre o conjugada, como ésteres, glicósidos y acilglicósidos de esteroles. Cada especie vegetal tiene su propio perfil cualitativo y ...
Marín-Valls, Roser (Fecha de defensa: 2021-10-01)
Biocatalysis gained importance in the latter half of the 20th century and its application in the pharmaceutical, food and chemical industries continues to expand nowadays. Enzymes catalyze chemical reactions in a highly ...
Limón Magaña, David (Fecha de defensa: 2017-07-21)
anostructured supramolecular hydrogels and gold nanoparticles, as two kinds of nanomaterials, were synthsized, characterized and evaluated for their potential as drug delivery systems. Two bis-imidazolium cationic ...
Guercetti, Julian (Fecha de defensa: 2023-10-25)
[eng] The current doctoral thesis titled “Microarray Strategies for Multiplexed Immunochemical Analysis” was carried out in the context of two research projects, expecting to develop multiplexed ligand-binding assays under ...
Antolin Fontes, Albert (Fecha de defensa: 2019-03-07)
The mitochondrial Seryl-tRNA Synthetase (SerRS2) is a member of the class II tRNA synthetase family. The mature enzyme catalyses the ligation of serine to tRNASer in mitochondria. During the process of constructing a model ...
Calatayud Robert, Sara (Fecha de defensa: 2021-12-20)
Proteins are composed of domains, a well-defined region within a protein that constitutes a stable, independently folding, compact structural unit, and that usually performs a specific function. During protein evolution, ...
Gutierrez Prat, Núria (Fecha de defensa: 2018-10-03)
Cells often need to respond to damaging internal and external stimuli. One of the pathways that is frequently activated by stress stimuli involves activation of the kinase p38alpha, which can phosphorylate different ...
Tatarski, Miloš (Fecha de defensa: 2018-09-21)
INTRODUCTION: For decades it was known that many species contain embryo specific linker histone H1 variants that replace the somatic H1 during early embryogenesis. This is especially important because the early embryo ...
Pérez Calm, Adrià (Fecha de defensa: 2023-07-28)
[eng] This thesis addresses molecular segregation in perylene-based systems, including lyotropic chromonic liquid crystals and water-in-water emulsions. These systems offer several advantages compared to conventional ...