IRBC-induced p53-dependent Cell Death in c-MYC-driven tumors mediated by loss of MCL1 

Domostegui Fernández, Ana (Date of defense: 2019-12-05)

The oncogene MYC is altered and its expression is deregulated in up to 70% of human cancers, including B cell neoplasms. Earlier studies in a mouse model of Eμ-MYC-driven B-cell lymphomas reported that oncogenic MYC relies ...