Soria Florido, María Trinidad (Date of defense: 2019-01-11)
Cardiovascular disease remains the first cause of death worldwide. Pharmacological trials and Mendelian randomization studies have failed to unequivocally prove an inverse association between HDL-C ...
Vais, Ricardo Silva dos Santos (Date of defense: 2019-12-13)
The γ-‐tubulin ring complex (γTuRC) is required to efficiently generate new microtubules (MT) in a process known as MT nucleation. In mitotic cells, MT nucleation by γTuRC occurs from the centrosome, ...
Bujaldon Ormaechea, Esther (Date of defense: 2019-10-04)
La hepatectomía parcial bajo isquemia-reperfusión (PH + I/R) es una estrategia que se utiliza comúnmente en la práctica clínica para reducir la hemorragia durante la resección del parénquima hepático. ...
Toribio Isaías, Luis Daniel (Date of defense: 2019-12-18)
The aim of this project is to structurally characterize proteins involved in bacterial signal transduction systems by applying X-ray crystallography. Bacteria use signal transduction systems to react ...
Zamora Ramírez, William J. (Date of defense: 2019-02-22)
Lipophilicity is a key physicochemical descriptor used to understand the biological profile of (bio)organic compounds, xenobiotics and a broad variety of biochemical, pharmacological, and toxicological ...
Sostoa Pomés, Jana de (Date of defense: 2019-05-31)
Oncolytic virus (OV)-based therapies have an emerging role in the treatment of solid tumors, involving both direct cell lysis and immunogenic cell death. Nonetheless, tumor- associated stroma limits the ...
Busquets Figueras, Oriol (Date of defense: 2019-12-20)
Molts estudis previs sobre el paper de les cinases c-JUN N-terminal (JNK) no tenien en compte les diferències existents en l’activitat de cadascuna de les isoformes. Això va provocar que les propostes ...
Rinaldi de Alvarenga, José Fernando (Date of defense: 2019-07-18)
Cooking made humans evolve. Cooking modified our gastrointestinal system, reducing the gut size and energy expenditure for digestion, which enabled the appearance of a more energy-dependent brain. Cooking ...
Bernat Peguera, Adrià (Date of defense: 2019-09-20)
La mayoría de los carcinomas escamosos de piel (cSCCs) se tratan con éxito mediante escisión quirúrgica. Sin embargo, el 5-8% de los casos desarrollan recurrencias, las cuales están asociadas a un ...
Castillo de la Peña, Yaiza M. (Date of defense: 2019-12-17)
Marine viruses are key components of marine microbial communities, as they influence the cellular abundances and the community structure of microbes, participate in their genetic exchange, and intervene ...