Novak, Ana (Date of defense: 2019-06-26)
Parenteral nutrition-associated liver dysfunction (PNALD) is one of the most severe long-term parenteral nutrition complications, which was attributed to the phytosterols, found in vegetable oil based ...
Hidalgo Martínez, Diego Alberto (Date of defense: 2017-07-10)
The thesis is presented as a compendium of publications and includes six different sections: General Introduction, Objectives, Results, General Discussion, Conclusions and References. The General ...
Miñarro Lleonar, Marina (Date of defense: 2023-02-24)
[eng] Advances in structural and molecular biology have favoured the rational development of novel drugs thru structure-based drug design (SBDD). Particularly, computational tools have proven to be rapid ...
Arroba Hidalgo, Ester (Date of defense: 2021-02-10)
The human leukocyte antigen-G (HLA-G) is a non-classic MHC class I molecule. It is called “non-classic” because it differs from classic MHC class I molecules due to its very low amount of polymorphism ...
Juton, Charlotte (Date of defense: 2023-03-09)
[eng] Childhood obesity is a global public health problem with aggravating consequences during adulthood, including cardiovascular disease, type 2 diabetes, musculoskeletal disorders, and some types of ...
Quintana Agustí, Mireia (Date of defense: 2019-09-30)
This thesis addresses three different subjects closely related. First, a phenotypic screening measuring cytotoxicity in the gastric cancer cell line HGC-27 is reported. Next, a targeted-based assay ...
Checa Raya, Javier (Date of defense: 2021-03-26)
INTRODUCTION: Pulmonary manifestations are the main cause of morbidity and mortality in more than 90 % of cystic fibrosis (CF) patients who exceed the neonatal period. The chronic immune-inflammatory ...
Baumann, Adrian (Date of defense: 2018-11-22)
Endocytosis and endosomal trafficking are of central meaning in all eukaryotic cells. It enables cells to rapidly modify their surface exposure of signalling complexes, nutrient and ion transporters, ...
Quifer Rada, Paola (Date of defense: 2017-06-26)
Beer is by far the most widely consumed alcoholic beverage in the world. Moderate alcohol consumption in general has been inversely associated with incident cardiovascular disease in observational ...
Izquierdo Villalba, Ismael (Date of defense: 2020-01-17)
G proteins transduce a myriad of signals from receptors at the plasma membrane. Recent reports point to a novel localization of G proteins at the mitochondria and other endomembranes where they regulate ...