Departament de Genètica, Microbiologia i Estadística

Recent Submissions

Biofilms microbianos: Virulencia e interacciones hongo-bacteria 

Arévalo Jaimes, Betsy Verónica (Date of defense: 2024-12-13)

[spa] En la naturaleza la mayoría de los microorganismos viven en comunidades protegidas por una matriz extracelular. Estas agrupaciones, denominadas biofilms, generalmente albergan múltiples especies de microorganismos ...

Population genomics of the nesting and foraging areas of the loggerhead turtle (Caretta caretta) facing climate change 

Luna Ortiz, Patricia Astrid (Date of defense: 2024-11-18)

[eng] Genomic techniques are increasingly being utilized in conservation biology, providing critical insights into the behavior, reproductive success, and various threats faced by vulnerable species. The loggerhead sea ...

Characterization of Hippo downstream effectors in the maintenance of planarian cellular identity 

Font Martín, Daniel (Date of defense: 2024-10-30)

[eng] The study of tissue renewal in adult organisms has widely been viewed as a source to uncover the triggers for the disruption of cell lineages in pathologies such as cancer. One of pathways involved in this process ...

Less, but more: Massive gene losses and expansions in appendicularians stretch the evolutionary limits of the FGF signalling pathway within chordates 

Sánchez Serna, Gaspar (Date of defense: 2024-10-14)

[eng] The extensive diversity of forms in the animal kingdom arises from a limited set of evolutionarily conserved genes that coordinate during embryonic development to build complex bodies. Consequently, minor variations ...

Study of early signaling events governing epithelial regeneration = Estudio de las señales tempranas que dirigen la regeneración de epitelios 

Esteban Collado, José (Date of defense: 2024-09-13)

[eng] The mechanisms through which cells communicate to initiate a regenerative response remains unsolved. It is established that Reactive Oxygen Species (ROS) are early signals released from injured cells that propagates ...

Of flatworms and genes: Systematics, hybridization and evolutionary history of the Corso-Sardinian Dugesia (Platyhelminthes, Tricladida) 

Dols Serrate, Daniel (Date of defense: 2024-07-18)

[eng] Planarian flatworms (Platyhelminthes, Tricladida), commonly referred to as triclads, constitute a diverse taxonomic group encompassing a wealth of species exhibiting a broad spectrum of phenotypic diversity. Triclads ...

L’exposició a virus presents en l’ambient: descripció del viroma i avaluació del risc 

Itarte Sorolla, Marta (Date of defense: 2024-07-19)

[cat] Existeix una gran diversitat de virus presents en l’ambient als quals els humans estem exposats, constituint l’exposoma víric. Les eines de vigilància ambiental, com ara l’epidemiologia basada en aigües residuals, ...

CERKL as a modulator gene of mitochondrial dynamics and stress response in the retina 

García Arroyo, Rocío (Date of defense: 2024-04-19)

[eng] Inherited Retinal Dystrophies (IRDs) are a clinically and genetically highly heterogeneous group of genetic pathologies characterized by progressive attrition of photoreceptor cells and other retinal neurons, which ...

Modificación enzimática de la celulosa para la producción de biomateriales 

Cabañas Romero, Lourdes Verónica (Date of defense: 2023-10-19)

[spa] La creciente preocupación por la sostenibilidad y el impacto ambiental de los derivados del petróleo ha impulsado el desarrollo de nuevos materiales basados en fuentes renovables y amigables con el medio ambiente. ...

Estudi de l’efecte dels canvis socials sobre la conducta de tres grups familiars de goril·les de plana occidental (Gorilla gorilla gorilla) captius. A la recerca d’indicadors conductuals de benestar 

Martínez Gutiérrez, Raquel (Date of defense: 2024-01-24)

[cat] Un dels pilars bàsics que componen la raó de ser dels parcs zoològics actuals és la conservació ex situ d’espècies amenaçades. Aquesta comesa, comporta el compliment d’una sèrie de requisits, entre ells, el de ...

An Omics World: Colonization and Adaptive Processes of Styela plicata 

Galià Camps, Carles (Date of defense: 2024-01-22)

[eng] In the last decades biological invasions have emerged as a global concern, as they impact local biodiversity by disrupting ecosystem functioning and ultimately affect human health, economy and wellness. In a climate ...

Role Of The Innate Immunity In The Etiopathogenesis of Primary Sjögren Syndrome: Influence Of Viral And Immunogenetic Factors Related To Cell Adhesion Molecules In Systemic Disease And Autoantibody Profile 

Gheitasi, Hoda (Date of defense: 2024-01-26)

[eng] Sjögren Syndrome is a systemic autoimmune disease that affects the exocrine glands, most notably the salivary and lacrimal glands, although it can affect other mucosal surfaces. Inflammation at these sites leads to ...

Relevant deubiquitinating enzymes in cilium formation and function in the retina: USP48 

Sánchez Bellver, Laura (Date of defense: 2023-12-15)

[eng] Ciliopathies encompass a broad group of heterogeneous inherited disorders associated with dysfunction of the cilium, a ubiquitous microtubule-based organelle that translates extracellular stimuli into cellular ...

Dimensionality reduction in multigroup data: applications in integrative omics 

Millapán Toledo, Carolina Andrea (Date of defense: 2023-12-18)

[eng] The idea of this research is to propose dimensionality reduction methods considering multi- groups in a dataset. In multivariate analysis, there are many multigroup methods, but they have different objectives than ...

Del cicle biològic a noves estratègies vacunals pel virus de l’hepatitis A 

Chavarria Miró, Gemma (Date of defense: 2023-10-30)

[cat] El virus de l'hepatitis A (HAV) s'allibera de cèl·lules infectades principalment embolcallat en membranes de la pròpia cèl·lula, formant partícules quasi embolcallades (eHAV). Es creu que la biogènesis d’eHAV podria ...

Study of expression levels in MECP2 related disorders using transcriptomics and proteomics: characterizing Rett syndrome and MECP2 duplication syndrome 

Pascual Alonso, Ainhoa (Date of defense: 2023-07-14)

[eng] MECP2 is a multifunctional gene involved in multiple processes such as transcription regulation, chromatin remodelling, splicing and miRNA regulation. Malfunction of MECP2 due to loss of function mutations leads to ...

Global evaluation of the fitness and virulence determinants in the phytopathogen Ralstonia solanacearum 

Pedro Jové, Roger de (Date of defense: 2023-05-19)

[eng] Losses to plant pathogens pose a major threat to global agriculture and food security worldwide. In the context of globalisation and climate change, the emergence and dispersion of pathogens resistant to conventional ...

Determining the Three-dimensional Structure of Genomes and Genomic Domains Integrating Chromosome Conformation Capture Data and Microscopy Images 

Castillo Andreo, David (Date of defense: 2023-03-01)

[eng] Microscopy and Chromosome Conformation Capture (3C) are the two main techniques for studying the three-dimensional (3D) organization of the genome. Microscopy, allowing the visualization of genomic loci in individual ...

Noves tècniques per al control i desinfecció de virus contaminants d’aigua 

Forés Gil, Eva (Date of defense: 2023-01-20)

[cat] Arrel de la necessitat de garantir la disponibilitat d’aigua en un context d’escassetat i assegurar-ne un bon ús que no suposi un risc microbiològic per la població, aquesta Tesi Doctoral ha estat centrada en ...

Bacteriófagos y movilización de genes de resistencia a antibióticos desde una perspectiva One-Health 

Blanco Picazo, Pedro (Date of defense: 2022-12-16)

[spa] En las últimas décadas la resistencia a antibióticos se ha convertido en uno de los principales problemas de salud pública a nivel global, y desde la iniciativa One-Health se han propuesto afrontar este problema, ...