Mostrando ítems 85-104 de 117
Antón Galindo, Ester (Fecha de defensa: 2021-09-17)
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impairments in social communication and interaction, as well as repetitive and restricted patterns of behaviour. Although growing evidence ...
Leiva Martinez, Carlos (Fecha de defensa: 2019-11-20)
Benthic organisms inhabiting the shallow waters of the Southern Ocean are considered excellent models to study evolutionary processes, population connectivity patterns, and adaptation. They have evolved in an extreme ...
Rojo Laguna, José Ignacio (Fecha de defensa: 2017-07-21)
Some animals have incredible regenerative abilities which kept researchers fascinating during decades. How these animals are able to regenerate missing parts and restore damaged tissues can give researchers insights in the ...
Planas Marqués, Marc (Fecha de defensa: 2020-10-30)
The plant pathogen Ralstonia solanacearum is the causal agent of the devastating disease known as bacterial wilt. This disease affects more than 200 plant species in over 50 families, including economically important crops ...
García Vázquez, David (Fecha de defensa: 2016-12-16)
CHAPTER 1: Reconstructing ancient Mediterranean crossroads in Deronectes diving beetles Aim: To reconstruct the evolutionary history of a genus of freshwater beetle with a pan- Mediterranean distribution, to test classic ...
González Sastre, Alejandro (Fecha de defensa: 2017-07-27)
En aquesta tesi, titulada “Regeneració i homeòstasi a les planàries: gens i vies de senyalització implicats en l'organogènesi”, s’aprofundeix en l’estudi dels processos responsables de l’organogènesi a la planària d’aigua ...
Vizcaya Molina, Elena (Fecha de defensa: 2018-12-19)
One of the most important questions in regenerative biology is how and when genes change expression to trigger regeneration programs. Resetting of gene expression patterns during injury responses is shaped by the coordinated ...
Sánchez Bellver, Laura (Fecha de defensa: 2023-12-15)
[eng] Ciliopathies encompass a broad group of heterogeneous inherited disorders associated with dysfunction of the cilium, a ubiquitous microtubule-based organelle that translates extracellular stimuli into cellular ...
López Aladid, Rubén (Fecha de defensa: 2022-10-20)
[spa] El pulmón siempre se ha considerado estéril. Sin embargo, el campo de la microbiota pulmonar se ha visto revolucionado por el avance de las técnicas moleculares. Cada individuo tiene un perfil de microbiota único, ...
Rosselló Xamena, Maria (Fecha de defensa: 2021-12-10)
El manteniment de l’homeòstasi en organismes adults és cabdal per la continuïtat dels individus; desregulacions d’aquest equilibri porten a l’aparició de malalties. La planària és un model d’estudi en regeneració i remodelació ...
Tell Martí, Gemma (Fecha de defensa: 2018-05-07)
El gen MC1R (codi OMIM: #155555) codifica pel receptor de la melanocortina 1 (MC1R) que s’expressa majoritàriament a la membrana dels melanòcits i està implicat en la regulació de la síntesi de melanina. El gen MC1R és ...
Ribó Gené, Sílvia (Fecha de defensa: 2017-12-01)
Childhood obesity and overweight can often cause severe complications, including hypertension, dyslipidemia, insulin resistance, type 2 diabetes, and non-alcoholic fatty liver disease, amongst other disorders. Several ...
Sousa, Nidia de (Fecha de defensa: 2017-07-17)
A successful cell renewal, which occurs throughout the life of an organism, relies on multiple events, including proliferation and differentiation of progenitor cell populations, and death of unnecessary cells. Out of the ...
Pappa, Stella (Fecha de defensa: 2019-04-10)
During neural development, signaling molecules and networks of expressed transcription factors cooperate to control cellular fate. Chromatin acting factors are essential players in cell proliferation and differentiation ...
Gheitasi, Hoda (Fecha de defensa: 2024-01-26)
[eng] Sjögren Syndrome is a systemic autoimmune disease that affects the exocrine glands, most notably the salivary and lacrimal glands, although it can affect other mucosal surfaces. Inflammation at these sites leads to ...
Pi Roig, Aina (Fecha de defensa: 2018-04-06)
Tbx5 is a transcription factor expressed in the developing eyes, heart and upper limbs. Mutations in human TBX5 cause Holt-Oram syndrome (HOS), a condition characterised by heart and upper limb malformations. In zebrafish, ...
Martínez-Gil, Núria (Fecha de defensa: 2021-03-12)
Osteoporosis is a complex disease characterized by low bone mass, microarchitectural deterioration, and increased fracture risk. It is the most common bone disease that affects more than 200 million people worldwide and ...
Barbanti, Anna (Fecha de defensa: 2021-09-23)
Conservation actions aim to preserve and recover animal and plant species using in-situ or ex- situ strategies. The first, aims to protect and sustain populations in their natural habitat, the second are implemented when ...
Murcia Rosero, Lada (Fecha de defensa: 2019-10-28)
Most human solid tumors present signs of genomic instability. Activated oncogenes have been proposed to induce genomic instability through the generation of replicative stress. In this thesis, we have sown that the expression ...
Martínez Puchol, Sandra (Fecha de defensa: 2021-02-18)
L’objectiu principal de la present tesi doctoral ha estat l’optimització i aplicació de procediments basats en la seqüenciació massiva per a la descripció del viroma associat a l’aigua residual i a altres mostres d’interès ...