Ferrández Roldán, Alfonso (Date of defense: 2021-02-22)
The bloom of genomic data has revealed a vast amount of gene losses across all life kingdoms. However, the impact of gene loss on the evolution of the mechanisms of embryo development remains an important ...
Shivalikanjli, Anu (Date of defense: 2021-04-06)
The broad objectives of this work are the identification of genes that contribute to the susceptibility to attention-deficit/hyperactivity disorder (ADHD) and cocaine dependence, two disorders that ...
Rovira Lorente, Paula (Date of defense: 2020-09-23)
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental, complex and highly heritable disorder characterised by age-inappropriate symptoms of inattention, impulsivity and hyperactivity ...
Pineda i Cirera, Laura (Date of defense: 2020-09-22)
Aquesta Tesi té com a objectiu principal contribuir a l’estudi i a la identificació de factors genètics i epigenètics de susceptibilitat a les addiccions i a trastorns comòrbids, tant en humans com en ...
Burguera Hernández, Demian (Date of defense: 2017-09-22)
In the present work, we studied the evolution of alternative splicing (AS) from different perspectives. First, we performed a preliminary analysis where we identified alternative exons with tissue-specific ...
Pino, V. Beatriz (Date of defense: 2022-07-15)
In the Drosophila larva, most of the juvenile tissues are made up of large polyploid cells fated to die during metamorphosis stage. The dorsal trunk of the tracheal system is composed mainly of these ...
Pascual Alonso, Ainhoa (Date of defense: 2023-07-14)
[eng] MECP2 is a multifunctional gene involved in multiple processes such as transcription regulation, chromatin remodelling, splicing and miRNA regulation. Malfunction of MECP2 due to loss of function ...
Rosselló Xamena, Maria (Date of defense: 2021-12-10)
El manteniment de l’homeòstasi en organismes adults és cabdal per la continuïtat dels individus; desregulacions d’aquest equilibri porten a l’aparició de malalties. La planària és un model d’estudi en ...
García Vernet, Raquel (Date of defense: 2022-05-06)
El objetivo global de esta tesis es ampliar el conocimiento sobre la biología y ecología del rorcual común, con foco principal en la población de rorcual común de Islandia. Dadas las numerosas incógnitas ...
Aísa Marín, Izarbe (Date of defense: 2022-05-13)
The transcription factor NR2E3 participates in photoreceptor cell fate determination as it functions as both transcriptional repressor of cone genes and activator of rod genes. Mutations in NR2E3 cause ...