Browsing Facultat de Medicina i Ciències de la Salut by Subject "576"

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Advanced physiomimetic models for in vitro studies on respiratory diseases

Marhuenda Segarra, Esther (Date of defense: 2022-07-21)

[spa] Las células se encuentran en un entorno concreto, específico para la función de cada órgano. En el caso de los pulmones, la matriz extracelular ha de tener unas propiedades físicas que les permitan soportar los ...

Developing exhaustion-resistant CAR-T cells for the treatment of solid tumors

Barbao Carrasco, Paula (Date of defense: 2024-12-02)

[eng] Adoptive cell therapy using Chimeric Antigen Receptor (CAR)-T cells has demonstrated remarkable results in patients with certain types of cancer. CARs are synthetic receptors designed to redirect T cells against ...

Mechanobiology of single cell migration on patterned fibronectin gradients

Fortunato, Isabela Corina Santos (Date of defense: 2024-11-18)

[eng] Directed cell migration along gradients of extracellular matrix (ECM) density – a process called haptotaxis – plays a central role in morphogenesis, the immune response, and cancer invasion. It is commonly assumed ...

Role of B-cell memory on CD38-targeting Human Leukocyte Antigen desensitization therapy in Highly sensitized kidney transplant candidates

Torija Recasens, Alba (Date of defense: 2024-07-24)

[eng] INTRODUCTION: Kidney transplantation stands as the best treatment for end-stage renal disease (ESRD), offering superior outcomes in comparison to any type of dialysis therapY. The benefits of kidney transplantation ...

Study of collective cell durotaxis as an active wetting phenomenon

Pallares Pallares, Macià Esteve (Date of defense: 2022-03-08)

Cell migration is essential to many biological processes. In adult organisms, it is crucial for wound healing, homeostasis, and immune response, whereas aberrant cell migration potentially leads to pathology. For example, ...